Molecular Mechanism and Structural Aspects of Transporter Associated with Antigen Processing Inhibition by the Cytomegalovirus Protein US6

The human cytomegalovirus (HCMV) has evolved a set of elegant strategies to evade host immunity. The HCMV-encoded type I glycoprotein US6 inhibits peptide trafficking from the cytosol into the endoplasmic reticulum and subsequent peptide loading of major histocompatibility complex I molecules by blo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2001-12, Vol.276 (51), p.48031-48039
Hauptverfasser:	Kyritsis, Christoph, Gorbulev, Stanislav, Hutschenreiter, Silke, Pawlitschko, Kurt, Abele, Rupert, Tampé, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - metabolism Adenosine Triphosphatases - metabolism Adenosine Triphosphate - metabolism Animals ATP-Binding Cassette Transporters - antagonists & inhibitors ATP-Binding Cassette Transporters - chemistry ATP-Binding Cassette Transporters - metabolism Base Sequence Cytomegalovirus DNA Primers Endoplasmic Reticulum - metabolism Insecta Protein Conformation Recombinant Proteins - metabolism RNA-Binding Proteins - physiology US6 protein Viral Proteins - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!