Neuro-immune-endocrine functional system and vascular pathology
A new interpretation of the response to injury by the nervous, immune and endocrine system is proposed, in order to integrate biochemical knowledge into the respective clinical areas. The discovery that the signaling molecules of the classical nervous, immune and endocrine systems, that is, the neur...
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| Veröffentlicht in: | Medical hypotheses 2001-11, Vol.57 (5), p.561-569 |
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| container_title | Medical hypotheses |
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| creator | Aller, M.A. Arias, J.L. Lorente, L. Nava, M.P. Durán, H.J. Arias, J. |
| description | A new interpretation of the response to injury by the nervous, immune and endocrine system is proposed, in order to integrate biochemical knowledge into the respective clinical areas. The discovery that the signaling molecules of the classical nervous, immune and endocrine systems, that is, the neurotransmitters, cytokines and hormones, respectively, are expressed and perceived by the three systems, has enabled us to establish a functional concept of these systems. The hypothetical integration of different pathological processes in a functional response made up by three phases, the immediate or nervous, intermediate or immune and late or endocrine ones, makes it possible to consider that all of them represent different forms of expression of a functional response whose meaning is always the same, that is, inflammation. If the functions that characterize each one of these three phases represent the activity of the nervous, immune and endocrine systems, the biochemical knowledge could be integrated into the functional meaning of each system. |
| doi_str_mv | 10.1054/mehy.2001.1408 |
| format | Article |
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The discovery that the signaling molecules of the classical nervous, immune and endocrine systems, that is, the neurotransmitters, cytokines and hormones, respectively, are expressed and perceived by the three systems, has enabled us to establish a functional concept of these systems. The hypothetical integration of different pathological processes in a functional response made up by three phases, the immediate or nervous, intermediate or immune and late or endocrine ones, makes it possible to consider that all of them represent different forms of expression of a functional response whose meaning is always the same, that is, inflammation. If the functions that characterize each one of these three phases represent the activity of the nervous, immune and endocrine systems, the biochemical knowledge could be integrated into the functional meaning of each system.</description><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Endocrine Glands - physiology</subject><subject>Endocrinology</subject><subject>Humans</subject><subject>Immune System - physiology</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Nervous System Physiological Phenomena</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. 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Miscellaneous investigative techniques</topic><topic>Vascular Diseases - pathology</topic><topic>Vascular Diseases - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aller, M.A.</creatorcontrib><creatorcontrib>Arias, J.L.</creatorcontrib><creatorcontrib>Lorente, L.</creatorcontrib><creatorcontrib>Nava, M.P.</creatorcontrib><creatorcontrib>Durán, H.J.</creatorcontrib><creatorcontrib>Arias, J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical hypotheses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aller, M.A.</au><au>Arias, J.L.</au><au>Lorente, L.</au><au>Nava, M.P.</au><au>Durán, H.J.</au><au>Arias, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neuro-immune-endocrine functional system and vascular pathology</atitle><jtitle>Medical hypotheses</jtitle><addtitle>Med Hypotheses</addtitle><date>2001-11-01</date><risdate>2001</risdate><volume>57</volume><issue>5</issue><spage>561</spage><epage>569</epage><pages>561-569</pages><issn>0306-9877</issn><eissn>1532-2777</eissn><abstract>A new interpretation of the response to injury by the nervous, immune and endocrine system is proposed, in order to integrate biochemical knowledge into the respective clinical areas. 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| ispartof | Medical hypotheses, 2001-11, Vol.57 (5), p.561-569 |
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| subjects | Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Endocrine Glands - physiology Endocrinology Humans Immune System - physiology Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous Nervous System Physiological Phenomena Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Vascular Diseases - pathology Vascular Diseases - physiopathology |
| title | Neuro-immune-endocrine functional system and vascular pathology |
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