Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus
The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moder...
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| Veröffentlicht in: | Neurology 2001-12, Vol.57 (11), p.2122-2125 |
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| container_issue | 11 |
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| container_title | Neurology |
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| creator | DEREX, L NIGHOGHOSSIAN, N PERINETTI, M HONNORAT, J TROUILLAS, P |
| description | The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA. |
| doi_str_mv | 10.1212/WNL.57.11.2122 |
| format | Article |
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No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA.</description><identifier>ISSN: 0028-3878</identifier><identifier>EISSN: 1526-632X</identifier><identifier>DOI: 10.1212/WNL.57.11.2122</identifier><identifier>PMID: 11739840</identifier><identifier>CODEN: NEURAI</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; Blood. Blood coagulation. 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No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Contraindications</subject><subject>Female</subject><subject>Heart Atria</subject><subject>Heart Ventricles</subject><subject>Humans</subject><subject>Infarction, Middle Cerebral Artery - drug therapy</subject><subject>Infusions, Intravenous</subject><subject>Intracranial Embolism - drug therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Recurrence</subject><subject>Thrombolytic Therapy</subject><subject>Thrombosis - drug therapy</subject><subject>Tissue Plasminogen Activator - administration & dosage</subject><subject>Tissue Plasminogen Activator - adverse effects</subject><subject>Treatment Outcome</subject><issn>0028-3878</issn><issn>1526-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLxDAUhYMozji6dSnd6K41j7ZpljL4gqKbEd2FNElptC-TFJl_b8oUZnW5nO-cezkAXCOYIIzw_edbmWQ0QSgJGz4Ba5ThPM4J_joFawhxEZOCFitw4dw3hEGk7BysEKKEFSlcg3LX2KGrhnbvjYx8o60Y95HpIyEnryPjZKO7oDhvhx8djcIb3XsX_RnfRFJYZcRsmzMmdwnOatE6fbXMDfh4etxtX-Ly_fl1-1DGkmDkY6aIzDUmlBKVMixULWuS5UyLnOYikwVTKCUqq6uMKFkxJSDGukpRQUmqZE424O6QO9rhd9LO8y48qttW9HqYHKeYpGnBUACTAyjt4JzVNR-t6YTdcwT53B8P_fGMcoT43F8w3CzJU9VpdcSXwgJwuwDCSdHWVvTSuCMXDhOEGfkHlqp5Og</recordid><startdate>20011211</startdate><enddate>20011211</enddate><creator>DEREX, L</creator><creator>NIGHOGHOSSIAN, N</creator><creator>PERINETTI, M</creator><creator>HONNORAT, J</creator><creator>TROUILLAS, P</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011211</creationdate><title>Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus</title><author>DEREX, L ; NIGHOGHOSSIAN, N ; PERINETTI, M ; HONNORAT, J ; TROUILLAS, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-9d3c6e23773d492adfcf3569ea676a5c89d143d5fb53dcb9da022eb418734dc63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Contraindications</topic><topic>Female</topic><topic>Heart Atria</topic><topic>Heart Ventricles</topic><topic>Humans</topic><topic>Infarction, Middle Cerebral Artery - drug therapy</topic><topic>Infusions, Intravenous</topic><topic>Intracranial Embolism - drug therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Recurrence</topic><topic>Thrombolytic Therapy</topic><topic>Thrombosis - drug therapy</topic><topic>Tissue Plasminogen Activator - administration & dosage</topic><topic>Tissue Plasminogen Activator - adverse effects</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DEREX, L</creatorcontrib><creatorcontrib>NIGHOGHOSSIAN, N</creatorcontrib><creatorcontrib>PERINETTI, M</creatorcontrib><creatorcontrib>HONNORAT, J</creatorcontrib><creatorcontrib>TROUILLAS, P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DEREX, L</au><au>NIGHOGHOSSIAN, N</au><au>PERINETTI, M</au><au>HONNORAT, J</au><au>TROUILLAS, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus</atitle><jtitle>Neurology</jtitle><addtitle>Neurology</addtitle><date>2001-12-11</date><risdate>2001</risdate><volume>57</volume><issue>11</issue><spage>2122</spage><epage>2125</epage><pages>2122-2125</pages><issn>0028-3878</issn><eissn>1526-632X</eissn><coden>NEURAI</coden><abstract>The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>11739840</pmid><doi>10.1212/WNL.57.11.2122</doi><tpages>4</tpages></addata></record> |
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| ispartof | Neurology, 2001-12, Vol.57 (11), p.2122-2125 |
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| language | eng |
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| source | Journals@Ovid Ovid Autoload; MEDLINE; Alma/SFX Local Collection |
| subjects | Aged Aged, 80 and over Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Contraindications Female Heart Atria Heart Ventricles Humans Infarction, Middle Cerebral Artery - drug therapy Infusions, Intravenous Intracranial Embolism - drug therapy Male Medical sciences Middle Aged Pharmacology. Drug treatments Recurrence Thrombolytic Therapy Thrombosis - drug therapy Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - adverse effects Treatment Outcome |
| title | Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus |
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