Expression and release of IL-18 binding protein in response to IFN-gamma

IL-18 and IL-18 binding protein (IL-18BP) are two newly described opponents in the cytokine network. Local concentrations of these two players may determine biological functions of IL-18 in the context of inflammation, infection, and cancer. As IL-18 appears to be involved in the pathogenesis of Cro...

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Veröffentlicht in:	The Journal of immunology (1950) 2001-12, Vol.167 (12), p.7038-7043
Hauptverfasser:	Paulukat, J, Bosmann, M, Nold, M, Garkisch, S, Kämpfer, H, Frank, S, Raedle, J, Zeuzem, S, Pfeilschifter, J, Mühl, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Butyrates - pharmacology Caco-2 Cells Carcinoma - genetics Carcinoma - metabolism Cell Line Cells, Cultured Colonic Neoplasms - genetics Colonic Neoplasms - metabolism g-Interferon Glycoproteins - biosynthesis Glycoproteins - genetics Humans Intercellular Signaling Peptides and Proteins Interferon-gamma - pharmacology interleukin 18-binding protein Interleukin-12 - pharmacology Interleukin-18 - pharmacology Isobutyrates Keratinocytes - metabolism Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Organ Culture Techniques RNA, Messenger - biosynthesis sodium butyrate Transcriptional Activation Tumor Cells, Cultured
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