Stimulation of extracellular signal-regulated kinase by pituitary adenylate cyclase-activating polypeptide in alpha T3-1 gonadotrophs

The putative hypophysiotropic factor pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates glycoprotein hormone alpha-subunit (alpha GSU) gene transcription and secretion in the clonal gonadotroph alpha T3-1 cell line. The specific signalling pathways regulating these actions of PACA...

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Veröffentlicht in:	Journal of endocrinology 2001-12, Vol.171 (3), p.R5-10
Hauptverfasser:	Fowkes, RC, Burch, J, Burrin, JM
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Butadienes - pharmacology Cell Culture Techniques Cell Line Enzyme Inhibitors - pharmacology Mice Mitogen-Activated Protein Kinases - metabolism Neuropeptides - antagonists & inhibitors Neuropeptides - pharmacology Nitriles - pharmacology Pituitary Adenylate Cyclase-Activating Polypeptide Pituitary Gland, Anterior - cytology Pituitary Gland, Anterior - drug effects Pituitary Gland, Anterior - enzymology
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