Geographic variations in prevalence and underdiagnosis of COPD : Results of the IBERPOC multicentre epidemiological study
To ascertain the prevalence, diagnostic level, and treatment of COPD in Spain through a multicenter study comprising seven different geographic areas. This is an epidemiologic, multicenter, population-based study conducted in seven areas of Spain. A total of 4,035 men and women (age range, 40 to 69...
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| Veröffentlicht in: | Chest 2000-10, Vol.118 (4), p.981-989 |
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| creator | SOBRADILLO PENA, Victor MIRAVITLLES, Marc GABRIEL, Rafael JIMENEZ-RUIZ, Carlos A VILLASANTE, Carlos MASA, Juan Fernando VIEJO, José Luis FERNANDEZ-FAU, Lorenzo |
| description | To ascertain the prevalence, diagnostic level, and treatment of COPD in Spain through a multicenter study comprising seven different geographic areas.
This is an epidemiologic, multicenter, population-based study conducted in seven areas of Spain. A total of 4,035 men and women (age range, 40 to 69 years) who were randomly selected from a target population of 236,412 subjects participated in the study.
Eligible subjects answered the European Commission for Steel and Coal questionnaire. Spirometry was performed, followed by a bronchodilator test when bronchial obstruction was present.
The prevalence of COPD was 9.1% (95% confidence interval [CI], 8.1 to 10.2%), 15% in smokers (95% CI, 12.8 to 17.1%), 12.8% in ex-smokers (95% CI, 10.7 to 14.8%), and 4.1% in nonsmokers (95% CI, 3.3 to 5.1%). The prevalence in men was 14.3% (95% CI, 12.8 to 15. 9%) and 3.9% in women (95% CI, 3.1 to 4.8%). Marked differences were observed between sexes in smoking; the percentage of nonsmokers was 23% in men and 76.3% in women (p 60 years old, had higher educational levels, had > 15 pack-year smoking history, or had symptoms of chronic bronchitis.
COPD is a very frequent disease in Spain, and presents significant geographic variations and a very low level of previous diagnosis and treatment, even in the most advanced cases. |
| doi_str_mv | 10.1378/chest.118.4.981 |
| format | Article |
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This is an epidemiologic, multicenter, population-based study conducted in seven areas of Spain. A total of 4,035 men and women (age range, 40 to 69 years) who were randomly selected from a target population of 236,412 subjects participated in the study.
Eligible subjects answered the European Commission for Steel and Coal questionnaire. Spirometry was performed, followed by a bronchodilator test when bronchial obstruction was present.
The prevalence of COPD was 9.1% (95% confidence interval [CI], 8.1 to 10.2%), 15% in smokers (95% CI, 12.8 to 17.1%), 12.8% in ex-smokers (95% CI, 10.7 to 14.8%), and 4.1% in nonsmokers (95% CI, 3.3 to 5.1%). The prevalence in men was 14.3% (95% CI, 12.8 to 15. 9%) and 3.9% in women (95% CI, 3.1 to 4.8%). Marked differences were observed between sexes in smoking; the percentage of nonsmokers was 23% in men and 76.3% in women (p<0.0001). The prevalence of COPD varied among the areas, ranging from 4.9% (95% CI, 3.2 to 7.0%) in the area of the lowest prevalence to 18% (95% CI, 14.8 to 21.2%) in the area of the highest. There was no previous diagnosis of COPD in 78.2% of cases (284 of 363). Only 49.3% of patients with severe COPD, 11.8% of patients with moderate COPD, and 10% of patients with mild COPD were receiving some kind of treatment for COPD. Multivariate analysis showed that individuals had a higher probability of having received a previous diagnosis of COPD if they lived in urban areas, were of male gender, were > 60 years old, had higher educational levels, had > 15 pack-year smoking history, or had symptoms of chronic bronchitis.
COPD is a very frequent disease in Spain, and presents significant geographic variations and a very low level of previous diagnosis and treatment, even in the most advanced cases.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.118.4.981</identifier><identifier>PMID: 11035667</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: American College of Chest Physicians</publisher><subject>Adult ; Age Distribution ; Aged ; Biological and medical sciences ; Chronic obstructive pulmonary disease, asthma ; Female ; Humans ; Lung Diseases, Obstructive - diagnosis ; Lung Diseases, Obstructive - epidemiology ; Male ; Medical sciences ; Middle Aged ; Odds Ratio ; Pneumology ; Prevalence ; Severity of Illness Index ; Sex Distribution ; Spain - epidemiology ; Spirometry ; Surveys and Questionnaires</subject><ispartof>Chest, 2000-10, Vol.118 (4), p.981-989</ispartof><rights>2000 INIST-CNRS</rights><rights>Copyright American College of Chest Physicians Oct 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1529550$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11035667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SOBRADILLO PENA, Victor</creatorcontrib><creatorcontrib>MIRAVITLLES, Marc</creatorcontrib><creatorcontrib>GABRIEL, Rafael</creatorcontrib><creatorcontrib>JIMENEZ-RUIZ, Carlos A</creatorcontrib><creatorcontrib>VILLASANTE, Carlos</creatorcontrib><creatorcontrib>MASA, Juan Fernando</creatorcontrib><creatorcontrib>VIEJO, José Luis</creatorcontrib><creatorcontrib>FERNANDEZ-FAU, Lorenzo</creatorcontrib><title>Geographic variations in prevalence and underdiagnosis of COPD : Results of the IBERPOC multicentre epidemiological study</title><title>Chest</title><addtitle>Chest</addtitle><description>To ascertain the prevalence, diagnostic level, and treatment of COPD in Spain through a multicenter study comprising seven different geographic areas.
This is an epidemiologic, multicenter, population-based study conducted in seven areas of Spain. A total of 4,035 men and women (age range, 40 to 69 years) who were randomly selected from a target population of 236,412 subjects participated in the study.
Eligible subjects answered the European Commission for Steel and Coal questionnaire. Spirometry was performed, followed by a bronchodilator test when bronchial obstruction was present.
The prevalence of COPD was 9.1% (95% confidence interval [CI], 8.1 to 10.2%), 15% in smokers (95% CI, 12.8 to 17.1%), 12.8% in ex-smokers (95% CI, 10.7 to 14.8%), and 4.1% in nonsmokers (95% CI, 3.3 to 5.1%). The prevalence in men was 14.3% (95% CI, 12.8 to 15. 9%) and 3.9% in women (95% CI, 3.1 to 4.8%). Marked differences were observed between sexes in smoking; the percentage of nonsmokers was 23% in men and 76.3% in women (p<0.0001). The prevalence of COPD varied among the areas, ranging from 4.9% (95% CI, 3.2 to 7.0%) in the area of the lowest prevalence to 18% (95% CI, 14.8 to 21.2%) in the area of the highest. There was no previous diagnosis of COPD in 78.2% of cases (284 of 363). Only 49.3% of patients with severe COPD, 11.8% of patients with moderate COPD, and 10% of patients with mild COPD were receiving some kind of treatment for COPD. Multivariate analysis showed that individuals had a higher probability of having received a previous diagnosis of COPD if they lived in urban areas, were of male gender, were > 60 years old, had higher educational levels, had > 15 pack-year smoking history, or had symptoms of chronic bronchitis.
COPD is a very frequent disease in Spain, and presents significant geographic variations and a very low level of previous diagnosis and treatment, even in the most advanced cases.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Female</subject><subject>Humans</subject><subject>Lung Diseases, Obstructive - diagnosis</subject><subject>Lung Diseases, Obstructive - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Pneumology</subject><subject>Prevalence</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Spain - epidemiology</subject><subject>Spirometry</subject><subject>Surveys and Questionnaires</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpd0FGL1DAQB_AgireePvsmQcS3rpOkSRPfdD3Pg4M9Dn0uaTLdzdEmNWkP9ttbdEXwaZjhxzDzJ-Q1gy0Tjf7gjljmLWN6W2-NZk_IhhnBKiFr8ZRsABivhDL8grwo5QHWnhn1nFwwBkIq1WzI6RrTIdvpGBx9tDnYOaRYaIh0yvhoB4wOqY2eLtFj9sEeYiqh0NTT3f7uC_1I77Esw_x7Mh-R3ny-ur_b7-i4DoPDOGekOAWPY0hDOgRnB1rmxZ9ekme9HQq-OtdL8uPr1ffdt-p2f32z-3RbTVyJuTIdZ77v6052fSM1eC0lszVaIRQopZWynQXVi6YHAU6DVg146ZmQUDuP4pK8_7N3yunnssbVjqE4HAYbMS2lbbioudFmhW__gw9pyXG9reUAtQRuYEVvzmjpRvTtlMNo86n9m-gK3p2BLeuvfbbRhfLPSW6kBPELc2eFLw</recordid><startdate>20001001</startdate><enddate>20001001</enddate><creator>SOBRADILLO PENA, Victor</creator><creator>MIRAVITLLES, Marc</creator><creator>GABRIEL, Rafael</creator><creator>JIMENEZ-RUIZ, Carlos A</creator><creator>VILLASANTE, Carlos</creator><creator>MASA, Juan Fernando</creator><creator>VIEJO, José Luis</creator><creator>FERNANDEZ-FAU, Lorenzo</creator><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20001001</creationdate><title>Geographic variations in prevalence and underdiagnosis of COPD : Results of the IBERPOC multicentre epidemiological study</title><author>SOBRADILLO PENA, Victor ; MIRAVITLLES, Marc ; GABRIEL, Rafael ; JIMENEZ-RUIZ, Carlos A ; VILLASANTE, Carlos ; MASA, Juan Fernando ; VIEJO, José Luis ; FERNANDEZ-FAU, Lorenzo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p263t-9b21dff4b5bf7580d8551a4ea336066866aba06f37f030c808670d5d13504cde3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Female</topic><topic>Humans</topic><topic>Lung Diseases, Obstructive - diagnosis</topic><topic>Lung Diseases, Obstructive - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Odds Ratio</topic><topic>Pneumology</topic><topic>Prevalence</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Spain - epidemiology</topic><topic>Spirometry</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SOBRADILLO PENA, Victor</creatorcontrib><creatorcontrib>MIRAVITLLES, Marc</creatorcontrib><creatorcontrib>GABRIEL, Rafael</creatorcontrib><creatorcontrib>JIMENEZ-RUIZ, Carlos A</creatorcontrib><creatorcontrib>VILLASANTE, Carlos</creatorcontrib><creatorcontrib>MASA, Juan Fernando</creatorcontrib><creatorcontrib>VIEJO, José Luis</creatorcontrib><creatorcontrib>FERNANDEZ-FAU, Lorenzo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SOBRADILLO PENA, Victor</au><au>MIRAVITLLES, Marc</au><au>GABRIEL, Rafael</au><au>JIMENEZ-RUIZ, Carlos A</au><au>VILLASANTE, Carlos</au><au>MASA, Juan Fernando</au><au>VIEJO, José Luis</au><au>FERNANDEZ-FAU, Lorenzo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Geographic variations in prevalence and underdiagnosis of COPD : Results of the IBERPOC multicentre epidemiological study</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2000-10-01</date><risdate>2000</risdate><volume>118</volume><issue>4</issue><spage>981</spage><epage>989</epage><pages>981-989</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>To ascertain the prevalence, diagnostic level, and treatment of COPD in Spain through a multicenter study comprising seven different geographic areas.
This is an epidemiologic, multicenter, population-based study conducted in seven areas of Spain. A total of 4,035 men and women (age range, 40 to 69 years) who were randomly selected from a target population of 236,412 subjects participated in the study.
Eligible subjects answered the European Commission for Steel and Coal questionnaire. Spirometry was performed, followed by a bronchodilator test when bronchial obstruction was present.
The prevalence of COPD was 9.1% (95% confidence interval [CI], 8.1 to 10.2%), 15% in smokers (95% CI, 12.8 to 17.1%), 12.8% in ex-smokers (95% CI, 10.7 to 14.8%), and 4.1% in nonsmokers (95% CI, 3.3 to 5.1%). The prevalence in men was 14.3% (95% CI, 12.8 to 15. 9%) and 3.9% in women (95% CI, 3.1 to 4.8%). Marked differences were observed between sexes in smoking; the percentage of nonsmokers was 23% in men and 76.3% in women (p<0.0001). The prevalence of COPD varied among the areas, ranging from 4.9% (95% CI, 3.2 to 7.0%) in the area of the lowest prevalence to 18% (95% CI, 14.8 to 21.2%) in the area of the highest. There was no previous diagnosis of COPD in 78.2% of cases (284 of 363). Only 49.3% of patients with severe COPD, 11.8% of patients with moderate COPD, and 10% of patients with mild COPD were receiving some kind of treatment for COPD. Multivariate analysis showed that individuals had a higher probability of having received a previous diagnosis of COPD if they lived in urban areas, were of male gender, were > 60 years old, had higher educational levels, had > 15 pack-year smoking history, or had symptoms of chronic bronchitis.
COPD is a very frequent disease in Spain, and presents significant geographic variations and a very low level of previous diagnosis and treatment, even in the most advanced cases.</abstract><cop>Northbrook, IL</cop><pub>American College of Chest Physicians</pub><pmid>11035667</pmid><doi>10.1378/chest.118.4.981</doi><tpages>9</tpages></addata></record> |
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| subjects | Adult Age Distribution Aged Biological and medical sciences Chronic obstructive pulmonary disease, asthma Female Humans Lung Diseases, Obstructive - diagnosis Lung Diseases, Obstructive - epidemiology Male Medical sciences Middle Aged Odds Ratio Pneumology Prevalence Severity of Illness Index Sex Distribution Spain - epidemiology Spirometry Surveys and Questionnaires |
| title | Geographic variations in prevalence and underdiagnosis of COPD : Results of the IBERPOC multicentre epidemiological study |
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