Potent Antipneumococcal Activity of Gemifloxacin Is Associated with Dual Targeting of Gyrase and Topoisomerase IV, an In Vivo Target Preference for Gyrase, and Enhanced Stabilization of Cleavable Complexes In Vitro

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commerc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2000-11, Vol.44 (11), p.3112-3117
Hauptverfasser:	HEATON, Victoria J, AMBLER, Jane E, FISHER, L. Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Ciprofloxacin - pharmacology DNA Gyrase DNA Topoisomerase IV DNA Topoisomerases, Type II DNA Topoisomerases, Type II - drug effects DNA Topoisomerases, Type II - genetics DNA Topoisomerases, Type II - metabolism Drug Resistance, Microbial - genetics Fluoroquinolones Gemifloxacin gyrA gene Humans Mechanisms of Action: Physiological Effects Medical sciences Microbial Sensitivity Tests Mutation Naphthyridines Naphthyridines - pharmacology parC gene Pharmacology. Drug treatments Streptococcus pneumoniae Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - enzymology Streptococcus pneumoniae - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!