Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats

Increased renal expression of monocyte chemoattractant protein-1 and osteopontin in ADPKD in rats. Human autosomal-dominant polycystic kidney disease (ADPKD) is variable in the rate of deterioration of renal function, with end-stage renal disease (ESRD) occurring in only approximately 50% of affecte...

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Veröffentlicht in:	Kidney international 2001-12, Vol.60 (6), p.2087-2096
Hauptverfasser:	Cowley, Benjamin D., Ricardo, Sharon D., Nagao, Shizuko, Diamond, Jonathan R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autosomal-dominant PKD Biological and medical sciences Chemokine CCL2 - genetics Chemokine CCL2 - metabolism cysts Female fibrosis Heterozygote Immunohistochemistry In Situ Hybridization inherited disease interstitial inflammation Kidney - metabolism Kidney - pathology Kidneys Macrophages - pathology Male Medical sciences Nephrology. Urinary tract diseases Osteopontin Polycystic Kidney, Autosomal Dominant - metabolism Polycystic Kidney, Autosomal Dominant - pathology Rats Rats, Inbred Strains Reference Values renal failure RNA, Messenger - metabolism Sex Characteristics Sialoglycoproteins - genetics Sialoglycoproteins - metabolism Tumors of the urinary system
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