A comparison of dynamic characteristics of fluconazole, itraconazole, and amphotericin B against Cryptococcus neoformans using time-kill methodology

This study evaluated the in vitro pharmacodynamics of fluconazole, itraconazole, and amphotericin B against Cryptococcus neoformans. MICs were determined for three clinical isolates according to NCCLS guidelines (M27). Time-kill studies were performed using antifungal concentrations of 0.25-32xMIC a...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2000-10, Vol.38 (2), p.87-93
Hauptverfasser:	Burgess, David S., Hastings, Rhonda W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - pharmacology Biological and medical sciences Cryptococcus neoformans - drug effects Fluconazole - pharmacology Humans Itraconazole - pharmacology Medical sciences Microbial Sensitivity Tests - methods Pharmacology. Drug treatments Time Factors
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