Differential effects of glutamate agonists and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats

In order to determine whether ionotropic (iGluRs) and metabotropic (mGluRs) glutamate receptor activation modulates oxytocin release in male rats, we investigated the effect of agonists of both types of glutamate receptors on oxytocin release from hypothalamus and posterior pituitary. Kainate and qu...

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Veröffentlicht in:	Endocrine 2001, Vol.15 (3), p.309-315
Hauptverfasser:	Pampillo, M, del Carmen Díaz, M, Duvilanski, B H, Rettori, V, Seilicovich, A, Lasaga, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Animals Aspartic Acid - pharmacology Endocrinology Excitatory Amino Acid Agonists - pharmacology Excitatory amino acids Glutamic acid receptors Glutamic acid receptors (ionotropic) Glutamic acid receptors (metabotropic) Hypothalamus Hypothalamus - drug effects Hypothalamus - metabolism In Vitro Techniques Male N-Methyl-D-aspartic acid receptors Oxytocin Oxytocin - metabolism Pituitary (posterior) Pituitary Gland, Posterior - drug effects Pituitary Gland, Posterior - metabolism Rats Rats, Wistar Receptor mechanisms Receptors, AMPA - agonists Receptors, Metabotropic Glutamate - metabolism Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid
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