Expression of BARF1 gene encoded by Epstein-Barr virus in nasopharyngeal carcinoma biopsies

We reported previously that the EBV BARF1 open reading frame encodes a Mr 31,000-33,000 protein (p31) with potential transforming and oncogenic properties. This gene was found capable of transforming both: (a) the rodent fibroblast lines Balbc/3T3 and NIH3T3 into cells producing aggressive tumors in...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2000-10, Vol.60 (19), p.5584-5588
Hauptverfasser:	DECAUSSIN, Gisèle, SBIH-LAMMALI, Fatima, DE TURENNE-TESSIER, Mireille, BOUGUERMOUH, Abdelmadjide, OOKA, Tadamasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BARF1 gene Biological and medical sciences Biopsy Cell Line Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - genetics Epstein-Barr Virus Infections - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Herpesvirus 4, Human - genetics Humans Immunohistochemistry Life Sciences Lymphocytes - metabolism Medical sciences Mice Mice, Nude Microbiology and Parasitology Molecular and cellular biology Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - virology Neoplasm Transplantation Open Reading Frames Otorhinolaryngology. Stomatology Protein Biosynthesis Reverse Transcriptase Polymerase Chain Reaction Transcription, Genetic Transplantation, Heterologous Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Viral Proteins - biosynthesis Viral Proteins - genetics Virology
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