Mucosal and Systemic Immune Activation Is Present in Human Immunodeficiency Virus—Exposed Seronegative Women

Immune parameters were analyzed in peripheral blood mononuclear cells (PBMC) and cervical mucosa biopsy specimens of human immunodeficiency virus (HIV)—seronegative women sexually exposed to HIV (exposed seronegative [ESN]), HIV-infected women, and healthy women without HIV exposure. HIV was not det...

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Veröffentlicht in:	The Journal of infectious diseases 2000-11, Vol.182 (5), p.1365-1374
Hauptverfasser:	Biasin, Mara, Lo Caputo, Sergio, Speciale, Livianna, Colombo, Fulvia, Racioppi, Luigi, Zagliani, Arianna, Blé, Claudio, Vichi, Francesca, Cianferoni, Luciano, Maria Masci, Anna, Luisa Villa, Maria, Ferrante, Pasquale, Mazzotta, Francesco, Clerici, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biopsies Complementary DNA Cytokines - biosynthesis Cytokines - genetics Female Genitalia Genitalia, Female - immunology Genitalia, Female - virology HIV HIV 1 HIV infections HIV Seronegativity - immunology Human viral diseases Humans Immunity, Mucosal Immunophenotyping Infectious diseases Interferon-gamma - secretion Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - virology Lymphocyte Activation Lymphocytes Major Articles Medical sciences Messenger RNA Mucosa Receptors, CCR5 - genetics Receptors, CXCR4 - genetics RNA, Messenger - analysis T lymphocytes T-Lymphocytes - immunology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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