Lack of coupling between GABA release and GABA synthesis in the rat brain via GABA(B) autoreceptors

GABA is synthesized within GABA terminals through a highly compartmentalized process in which glial-derived glutamine is a major precursor and its release is modulated by GABA(B) autoreceptors. The aim of this work was to ascertain whether or not GABA synthesis and release are coupled in the rat bra...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Amino acids 2000, Vol.19 (1), p.63-77
Hauptverfasser:	Aguilar-García, A, González-Frankenberger, B, Ramón-Frías, T, Méndez-Franco, B J, Pérez-de la Mora, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism GABA-B Receptor Agonists gamma-Aminobutyric Acid - biosynthesis gamma-Aminobutyric Acid - metabolism Glutamine - metabolism Ligands Male Rats Rats, Wistar Receptors, GABA-B - metabolism Tritium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!