Risk of venous thromboembolism in carriers of factor V Leiden with a concomitant inherited thrombophilic defect: a retrospective analysis

Factor V Leiden is the most common genetic defect associated with venous thromboembolism. Its clinical expression is limited and shows a wide intrafamilial and interfamilial variation, which might be explained by the influence of other genetic risk factors. We retrospectively studied 226 patients wi...

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Veröffentlicht in:	Blood coagulation & fibrinolysis 2001-12, Vol.12 (8), p.713-720
Hauptverfasser:	Meinardi, J R, Middeldorp, S, de Kam, P J, Koopman, M M. W, van Pampus, E C. M, Hamulyák, K, Prins, M H, Büller, H R, van der Meer, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Factor V - genetics Family Health Female Hematologic and hematopoietic diseases Heterozygote Humans Male Medical sciences Middle Aged Platelet diseases and coagulopathies Pregnancy Prevalence Regression Analysis Retrospective Studies Risk Factors Thromboembolism - etiology Thromboembolism - genetics Thrombophilia - complications Thrombophilia - genetics Venous Thrombosis - etiology Venous Thrombosis - genetics
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