The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus

Human papillomavirus type 16 (HPV16) infects cervical epithelium and is associated with the majority of cervical cancers. The E1E4 protein of HPV16 but not those of HPV1 or HPV6 was found to associate with a novel member of the DEAD box protein family of RNA helicases through sequences in its C term...

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Veröffentlicht in:	Journal of virology 2000-11, Vol.74 (21), p.10081-10095
Hauptverfasser:	Doorbar, J, Elston, R C, Napthine, S, Raj, K, Medcalf, E, Jackson, D, Coleman, N, Griffin, H M, Masterson, P, Stacey, S, Mengistu, Y, Dunlop, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Nucleus - metabolism Cytoplasm - metabolism DEAD-box RNA Helicases Gene Expression Regulation, Viral HeLa Cells Humans Molecular Sequence Data Nuclear Proteins - metabolism Oncogene Proteins, Fusion - chemistry Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Papillomaviridae - genetics Papillomaviridae - metabolism Papillomaviridae - pathogenicity Papillomavirus Infections - virology Ribosomes - metabolism RNA Helicases - chemistry RNA Helicases - genetics RNA Helicases - metabolism RNA, Messenger - metabolism Sequence Analysis, DNA Sequence Homology, Amino Acid Tumor Cells, Cultured Tumor Virus Infections - virology Two-Hybrid System Techniques Viral Proteins
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