Peripheral blood lymphocytes muscarinic cholinergic receptor subtypes in Alzheimer's disease: a marker of cholinergic dysfunction?

Muscarinic M2–M5 muscarinic cholinergic receptors were investigated in peripheral blood lymphocytes of patients with mild cognitive impairment of the Alzheimer's type (MCIAT), probable Alzheimer's disease (AD) and probable vascular dementia (VaD). [ 3H]- N-methyl scopolamine (NMS) in the p...

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Veröffentlicht in:	Journal of neuroimmunology 2001-12, Vol.121 (1), p.126-131
Hauptverfasser:	Tayebati, S.K, Amenta, F, Amici, S, El-Assouad, D, Gallai, V, Ricci, A, Parnetti, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - immunology Alzheimer Disease - physiopathology Alzheimer's disease Biomarkers Dementia, Vascular - immunology Female Humans In Vitro Techniques Lymphocytes Lymphocytes - chemistry Male Middle Aged MMSE Muscarinic receptors N-Methylscopolamine - metabolism N-Methylscopolamine - pharmacology Parasympatholytics - metabolism Parasympatholytics - pharmacology Radioligand Assay Receptor, Muscarinic M2 Receptor, Muscarinic M3 Receptor, Muscarinic M4 Receptor, Muscarinic M5 Receptors, Muscarinic - analysis Tritium
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