Effects of a high polyunsaturated fat diet and vitamin E supplementation on high-density lipoprotein oxidation in humans

Oxidative modification of high-density lipoproteins (HDL) impairs several biologic functions critical to its role in reverse cholesterol transport. We therefore investigated the effect of dietary polyunsaturated fat and vitamin E on the kinetics of HDL oxidation. Ten subjects were fed sequentially:...

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Veröffentlicht in:	Atherosclerosis 2001-12, Vol.159 (2), p.459-466
Hauptverfasser:	Schnell, James W., Anderson, Rachel A., Stegner, Jane E., Schindler, Stephen P., Weinberg, Richard B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cholesterol, HDL - blood Cholesterol, LDL - blood Dietary Fats, Unsaturated - administration & dosage Dietary Supplements Fatty Acids - analysis Fatty Acids - metabolism Female Fluorescence spectroscopy High-density lipoproteins Humans Lipid oxidation Lipid Peroxidation - drug effects Lipoproteins, HDL - analysis Lipoproteins, HDL - metabolism Low-density lipoproteins Medical sciences Monounsaturated fatty acids Polyunsaturated fatty acids Probability Prospective Studies Sensitivity and Specificity Triglycerides - blood Vitamin E Vitamin E - administration & dosage α-Tocopherol
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