Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling

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Bibliographische Detailangaben
Veröffentlicht in:	Nature genetics 2000-10, Vol.26 (2), p.146-147
Hauptverfasser:	Liu, Wanguo, Dong, Xiangyang, Mai, Ming, Seelan, Ratnam S., Taniguchi, Ken, Krishnadath, Kausilia K., Halling, Kevin C., Cunningham, Julie M., Qian, Chiping, Christensen, Eric, Roche, Patrick C., Smith, David I., Thibodeau, Stephen N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal Genetics and Genomics Axin Protein Base Pair Mismatch - genetics beta Catenin Biological and medical sciences Biomedical and Life Sciences Biomedicine brief-communication Cancer Research Cell Line Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Colorectal cancer Colorectal Neoplasms - genetics Complications and side effects Cytoskeletal Proteins - biosynthesis Cytoskeletal Proteins - genetics Cytoskeletal Proteins - physiology Diagnosis DNA mismatch repair DNA Mutational Analysis DNA repair DNA Repair - genetics Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gene Function Gene mutations Genes, Reporter Genetic aspects Human Genetics Humans Medical sciences Molecular and cellular biology Mutation Physiological aspects Risk factors Signal Transduction Stomach. Duodenum. Small intestine. Colon. Rectum. Anus TCF Transcription Factors Trans-Activators Transcription Factor 7-Like 2 Protein Transcription Factors - physiology Transfection Tumors
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