Inhibition of IFN-γ Signaling by an Epstein-Barr Virus Immediate-Early Protein

Viruses have evolved elaborate mechanisms to target many aspects of the host's immune response. The cytokine IFN-γ plays a central role in resistance of the host to infection via direct antiviral effects as well as modulation of the immune response. In this study, we demonstrate that the Epstei...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2001-11, Vol.15 (5), p.787-799
Hauptverfasser:	Morrison, Thomas E, Mauser, Amy, Wong, Athena, Ting, Jenny P.-Y, Kenney, Shannon C
Format:	Artikel
Sprache:	eng
Schlagworte:	BZLF1 protein DNA-Binding Proteins - immunology Epstein-Barr virus Epstein-Barr Virus Infections - immunology g-Interferon g-Interferon receptors HeLa Cells Herpesvirus 4, Human - immunology Humans immediate early proteins Immunity Interferon-gamma - immunology Signal Transduction - immunology Trans-Activators - immunology Viral Proteins
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