Randomized study of antibodies to IFN-gamma and TNF-alpha in secondary progressive multiple sclerosis

Studies of cytokines in multiple sclerosis (MS) have shown that immune mechanisms connected with disturbance of the synthesis of cytokines probably play critical roles in the initiation and prolongation of MS. In a double-blind, placebo-controlled trial, 45 patients with active secondary progressive...

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Veröffentlicht in:	Multiple sclerosis 2001-10, Vol.7 (5), p.277-284
Hauptverfasser:	Skurkovich, S, Boiko, A, Beliaeva, I, Buglak, A, Alekseeva, T, Smirnova, N, Kulakova, O, Tchechonin, V, Gurova, O, Deomina, T, Favorova, O O, Skurkovic, B, Gusev, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - pharmacology Cytokines - immunology Double-Blind Method Female g-Interferon Goats Humans Interferon-gamma - immunology Magnetic Resonance Imaging Multiple Sclerosis, Chronic Progressive - immunology Multiple Sclerosis, Chronic Progressive - pathology Multiple Sclerosis, Chronic Progressive - therapy Treatment Outcome Tumor Necrosis Factor-alpha - immunology
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