Effects of nucleotides on N-acetyl-d-glucosamine 2-epimerases (renin-binding proteins): comparative biochemical studies

Renin-binding protein (RnBP) is an endogenous renin inhibitor originally isolated from porcine kidney as a complex of renin, so-called high molecular weight (HMW) renin. Our recent studies demonstrated that human RnBP is the enzyme N-acetyl-D-glucosamine (GlcNAc) 2-epimerase [Takahashi, S. et al. (1...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 2001-12, Vol.130 (6), p.815-821
Hauptverfasser:	Takahashi, S, Hori, K, Takahashi, K, Ogasawara, H, Tomatsu, M, Saito, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals Carbohydrate Epimerases - drug effects Carbohydrate Epimerases - isolation & purification Carbohydrate Epimerases - pharmacology Carrier Proteins - drug effects Carrier Proteins - isolation & purification Carrier Proteins - pharmacology Deoxyadenine Nucleotides - pharmacology Deoxyguanine Nucleotides - pharmacology Humans Hydrolysis - drug effects Nucleotides - pharmacology Rats Recombinant Proteins - drug effects Recombinant Proteins - isolation & purification Recombinant Proteins - pharmacology Renin - antagonists & inhibitors Swine Thermolysin - antagonists & inhibitors
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