Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine
A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations. The two study groups were compared for pain of infiltration (100 m...
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Veröffentlicht in: | The Journal of emergency medicine 2001-11, Vol.21 (4), p.375-379 |
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creator | Bartfield, Joel M May-Wheeling, Holly E Raccio-Robak, Nancy Lai, Shin-Yi |
description | A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations. The two study groups were compared for pain of infiltration (100 mm visual analog scale) and need for additional anesthesia. Pain scores were compared by a Mann Whitney Independent Rank Sum test and need for additional anesthesia by a Fishers Exact test. A total of 52 subjects (26 per group) were analyzed. The groups were similar in demographics and wound characteristics. The median pain score for BA, 7.5 mm, was less than for LID, 19.5 mm (
p = 0.049). Although more patients receiving BA required additional anesthesia as compared to LID (8/26 versus 2/26), this difference did not reach statistical significance. BA is a reasonable alternative local anesthetic to LID for patients who are allergic to LID. |
doi_str_mv | 10.1016/S0736-4679(01)00404-8 |
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p = 0.049). Although more patients receiving BA required additional anesthesia as compared to LID (8/26 versus 2/26), this difference did not reach statistical significance. BA is a reasonable alternative local anesthetic to LID for patients who are allergic to LID.</description><subject>Adult</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anesthetics, Local</subject><subject>benzyl alcohol</subject><subject>Benzyl Alcohol - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Double-Blind Method</subject><subject>Epinephrine - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Lacerations - surgery</subject><subject>lidocaine</subject><subject>Lidocaine - therapeutic use</subject><subject>local</subject><subject>Local anesthesia. Pain (treatment)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>penetrating</subject><subject>Prospective Studies</subject><subject>wounds</subject><issn>0736-4679</issn><issn>2352-5029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9PwyAYh4nRuDn9CJpeNHqoQikFTkYX_yVLdlDPhNGXDNO1E7qZ-ellW-MSL15eDr_nxwsPQqcEXxNMiptXzGmR5gWXl5hcYZzjPBV7qJ9RlqUMZ3If9X-RHjoK4QNjwrEgh6hHCM8EL2gfje-h_l5Via5MM22q5Mu10wTmrob51MeZ6JDoOsYt-Fq3bglJ2ySVKxuj1_Ff_hgdWF0FOOnOAXp_fHgbPqej8dPL8G6UGipJmzIrpKbGFBMGsphMhNWclrjMGCtkKYjgnGEmDLUyz6TVgkkrRaHLGBibZ3SALrb3zn3zuYDQqpkLBqpK19AsguIZJTh-OIJsCxrfhODBqrl3M-1XimC1Nqk2JtVak8JEbUwqEXtn3YLFZAblrtWpi8B5B-hgdGW9ro0LO45SznPGIne75SDqWDrwKhgHtYHSeTCtKhv3z1N-ABftj_0</recordid><startdate>20011101</startdate><enddate>20011101</enddate><creator>Bartfield, Joel M</creator><creator>May-Wheeling, Holly E</creator><creator>Raccio-Robak, Nancy</creator><creator>Lai, Shin-Yi</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011101</creationdate><title>Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine</title><author>Bartfield, Joel M ; May-Wheeling, Holly E ; Raccio-Robak, Nancy ; Lai, Shin-Yi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-5f89a3cc6b5e96bb8fa73d0d25569d818775058c3f9429fa859f986ad877cf423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anesthetics, Local</topic><topic>benzyl alcohol</topic><topic>Benzyl Alcohol - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Double-Blind Method</topic><topic>Epinephrine - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Lacerations - surgery</topic><topic>lidocaine</topic><topic>Lidocaine - therapeutic use</topic><topic>local</topic><topic>Local anesthesia. Pain (treatment)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>penetrating</topic><topic>Prospective Studies</topic><topic>wounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bartfield, Joel M</creatorcontrib><creatorcontrib>May-Wheeling, Holly E</creatorcontrib><creatorcontrib>Raccio-Robak, Nancy</creatorcontrib><creatorcontrib>Lai, Shin-Yi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bartfield, Joel M</au><au>May-Wheeling, Holly E</au><au>Raccio-Robak, Nancy</au><au>Lai, Shin-Yi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine</atitle><jtitle>The Journal of emergency medicine</jtitle><addtitle>J Emerg Med</addtitle><date>2001-11-01</date><risdate>2001</risdate><volume>21</volume><issue>4</issue><spage>375</spage><epage>379</epage><pages>375-379</pages><issn>0736-4679</issn><eissn>2352-5029</eissn><coden>JEMMDO</coden><abstract>A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations. 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subjects | Adult Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Local benzyl alcohol Benzyl Alcohol - therapeutic use Biological and medical sciences Double-Blind Method Epinephrine - therapeutic use Female Humans Lacerations - surgery lidocaine Lidocaine - therapeutic use local Local anesthesia. Pain (treatment) Male Medical sciences Middle Aged penetrating Prospective Studies wounds |
title | Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine |
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