Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine

A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations. The two study groups were compared for pain of infiltration (100 m...

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Veröffentlicht in:The Journal of emergency medicine 2001-11, Vol.21 (4), p.375-379
Hauptverfasser: Bartfield, Joel M, May-Wheeling, Holly E, Raccio-Robak, Nancy, Lai, Shin-Yi
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container_issue 4
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container_title The Journal of emergency medicine
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creator Bartfield, Joel M
May-Wheeling, Holly E
Raccio-Robak, Nancy
Lai, Shin-Yi
description A randomized, prospective, double-blind study comparing benzyl alcohol with epinephrine, 1:100,000 (BA), and lidocaine with epinephrine, 1:100,000 (LID), as local anesthetics was carried out on adult patients with simple lacerations. The two study groups were compared for pain of infiltration (100 mm visual analog scale) and need for additional anesthesia. Pain scores were compared by a Mann Whitney Independent Rank Sum test and need for additional anesthesia by a Fishers Exact test. A total of 52 subjects (26 per group) were analyzed. The groups were similar in demographics and wound characteristics. The median pain score for BA, 7.5 mm, was less than for LID, 19.5 mm ( p = 0.049). Although more patients receiving BA required additional anesthesia as compared to LID (8/26 versus 2/26), this difference did not reach statistical significance. BA is a reasonable alternative local anesthetic to LID for patients who are allergic to LID.
doi_str_mv 10.1016/S0736-4679(01)00404-8
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subjects Adult
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anesthetics, Local
benzyl alcohol
Benzyl Alcohol - therapeutic use
Biological and medical sciences
Double-Blind Method
Epinephrine - therapeutic use
Female
Humans
Lacerations - surgery
lidocaine
Lidocaine - therapeutic use
local
Local anesthesia. Pain (treatment)
Male
Medical sciences
Middle Aged
penetrating
Prospective Studies
wounds
title Benzyl alcohol with epinephrine as an alternative to lidocaine with epinephrine
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