Regional differences in waiting time to pregnancy among fertile couples from four European cities
BACKGROUND: A previous European study found a longer time to pregnancy (TTP) among fertile women from Paris compared with women from other Western European countries. A co-ordinated, cross-sectional study of pregnant couples from Denmark (Copenhagen), France (Paris), Scotland (Edinburgh) and Finland...
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creator | Jensen, T.K. Slama, R. Ducot, B. Suominen, J. Cawood, E.H.H. Andersen, A.G. Eustache, F. Irvine, S. Auger, S. Jouannet, P. Vierula, M. Jørgensen, N. Toppari, J. Skakkebaek, N.E. Keiding, N. Spira, A. |
description | BACKGROUND: A previous European study found a longer time to pregnancy (TTP) among fertile women from Paris compared with women from other Western European countries. A co-ordinated, cross-sectional study of pregnant couples from Denmark (Copenhagen), France (Paris), Scotland (Edinburgh) and Finland (Turku) was therefore undertaken to assess differences in waiting TTP among couples from these cities. METHODS: Pregnant women were invited to participate when they showed up for their first antenatal visit in one of the four centres. Inclusion criteria included that their partner was 20–45 years of age and born in the country in which he was currently living and that the pregnancy was achieved without fertility treatment. Both partners filled in a questionnaire and the man underwent a physical examination and delivered a semen sample (Turku: n = 237, Copenhagen: n = 302, Edinburgh: n = 212, Paris: n = 191). RESULTS: French couples had a decreased probability of conception compared with couples from the other three countries, although only after adjustment for confounders. No significant differences between couples from the three other countries were found. CONCLUSION: The observed geographical differences in TTP remain unexplained and were not due to differences in semen quality, but may be caused by varying exposures to environmental factors or psychological distress. In addition, selection bias due to the low participation rates cannot be ruled out. Future studies examining the causes for geographical differences in TTP are needed. |
doi_str_mv | 10.1093/humrep/16.12.2697 |
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A co-ordinated, cross-sectional study of pregnant couples from Denmark (Copenhagen), France (Paris), Scotland (Edinburgh) and Finland (Turku) was therefore undertaken to assess differences in waiting TTP among couples from these cities. METHODS: Pregnant women were invited to participate when they showed up for their first antenatal visit in one of the four centres. Inclusion criteria included that their partner was 20–45 years of age and born in the country in which he was currently living and that the pregnancy was achieved without fertility treatment. Both partners filled in a questionnaire and the man underwent a physical examination and delivered a semen sample (Turku: n = 237, Copenhagen: n = 302, Edinburgh: n = 212, Paris: n = 191). RESULTS: French couples had a decreased probability of conception compared with couples from the other three countries, although only after adjustment for confounders. No significant differences between couples from the three other countries were found. CONCLUSION: The observed geographical differences in TTP remain unexplained and were not due to differences in semen quality, but may be caused by varying exposures to environmental factors or psychological distress. In addition, selection bias due to the low participation rates cannot be ruled out. Future studies examining the causes for geographical differences in TTP are needed.</description><identifier>ISSN: 0268-1161</identifier><identifier>EISSN: 1460-2350</identifier><identifier>DOI: 10.1093/humrep/16.12.2697</identifier><identifier>PMID: 11726598</identifier><identifier>CODEN: HUREEE</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adult ; Age Factors ; Biological and medical sciences ; Cross-Sectional Studies ; Denmark - epidemiology ; Educational Status ; Environment ; environmental health ; Female ; Fertility ; Finland - epidemiology ; France - epidemiology ; Fundamental and applied biological sciences. Psychology ; Humans ; Infertility - epidemiology ; Infertility - etiology ; Male ; Middle Aged ; Mother. Fetoplacental unit. Mammary gland. Milk ; Parity ; population surveillance ; Pregnancy ; pregnancy rate ; Pregnancy. Parturition. Lactation ; Scotland - epidemiology ; Semen - physiology ; Sperm Count ; Stress, Psychological ; Surveys and Questionnaires ; Time Factors ; Vertebrates: reproduction</subject><ispartof>Human reproduction (Oxford), 2001-12, Vol.16 (12), p.2697-2704</ispartof><rights>European Society of Human Reproduction and Embryology 2001</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c513t-1aa10582cd2751f0a9890d798039540448d35daeddd38fb7e68f4ce1ad9b40d03</citedby><cites>FETCH-LOGICAL-c513t-1aa10582cd2751f0a9890d798039540448d35daeddd38fb7e68f4ce1ad9b40d03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13377832$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11726598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jensen, T.K.</creatorcontrib><creatorcontrib>Slama, R.</creatorcontrib><creatorcontrib>Ducot, B.</creatorcontrib><creatorcontrib>Suominen, J.</creatorcontrib><creatorcontrib>Cawood, E.H.H.</creatorcontrib><creatorcontrib>Andersen, A.G.</creatorcontrib><creatorcontrib>Eustache, F.</creatorcontrib><creatorcontrib>Irvine, S.</creatorcontrib><creatorcontrib>Auger, S.</creatorcontrib><creatorcontrib>Jouannet, P.</creatorcontrib><creatorcontrib>Vierula, M.</creatorcontrib><creatorcontrib>Jørgensen, N.</creatorcontrib><creatorcontrib>Toppari, J.</creatorcontrib><creatorcontrib>Skakkebaek, N.E.</creatorcontrib><creatorcontrib>Keiding, N.</creatorcontrib><creatorcontrib>Spira, A.</creatorcontrib><title>Regional differences in waiting time to pregnancy among fertile couples from four European cities</title><title>Human reproduction (Oxford)</title><addtitle>Hum. Reprod</addtitle><addtitle>Hum. Reprod</addtitle><description>BACKGROUND: A previous European study found a longer time to pregnancy (TTP) among fertile women from Paris compared with women from other Western European countries. A co-ordinated, cross-sectional study of pregnant couples from Denmark (Copenhagen), France (Paris), Scotland (Edinburgh) and Finland (Turku) was therefore undertaken to assess differences in waiting TTP among couples from these cities. METHODS: Pregnant women were invited to participate when they showed up for their first antenatal visit in one of the four centres. Inclusion criteria included that their partner was 20–45 years of age and born in the country in which he was currently living and that the pregnancy was achieved without fertility treatment. Both partners filled in a questionnaire and the man underwent a physical examination and delivered a semen sample (Turku: n = 237, Copenhagen: n = 302, Edinburgh: n = 212, Paris: n = 191). RESULTS: French couples had a decreased probability of conception compared with couples from the other three countries, although only after adjustment for confounders. No significant differences between couples from the three other countries were found. CONCLUSION: The observed geographical differences in TTP remain unexplained and were not due to differences in semen quality, but may be caused by varying exposures to environmental factors or psychological distress. In addition, selection bias due to the low participation rates cannot be ruled out. Future studies examining the causes for geographical differences in TTP are needed.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Cross-Sectional Studies</subject><subject>Denmark - epidemiology</subject><subject>Educational Status</subject><subject>Environment</subject><subject>environmental health</subject><subject>Female</subject><subject>Fertility</subject><subject>Finland - epidemiology</subject><subject>France - epidemiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Infertility - epidemiology</subject><subject>Infertility - etiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mother. Fetoplacental unit. Mammary gland. Milk</subject><subject>Parity</subject><subject>population surveillance</subject><subject>Pregnancy</subject><subject>pregnancy rate</subject><subject>Pregnancy. Parturition. Lactation</subject><subject>Scotland - epidemiology</subject><subject>Semen - physiology</subject><subject>Sperm Count</subject><subject>Stress, Psychological</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><subject>Vertebrates: reproduction</subject><issn>0268-1161</issn><issn>1460-2350</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMGKFDEQhoMo7rj6AF4kFz3Zs6mkO0kfZV1dYURYFMRLyCSVMdrdaZNudN_eLDO4V09VFN__F3yEPAe2BdaLi-_rmHG-ALkFvuWyVw_IBlrJGi469pBsGJe6AZBwRp6U8oOxumr5mJwBKC67Xm-IvcFDTJMdqI8hYMbJYaFxor9tXOJ0oEsckS6JzhkPk53cLbVjqvfKLnFA6tI6DzUSchppSGumV2tOM9qJutqA5Sl5FOxQ8NlpnpMv764-X143u0_vP1y-2TWuA7E0YC2wTnPnueogMNvrnnnVayb6rmVtq73ovEXvvdBhr1Dq0DoE6_t9yzwT5-TVsXfO6deKZTFjLA6HwU6Y1mIUF0xLgArCEXQ5lZIxmDnH0eZbA8zceTVHrwakAW7uvNbMi1P5uh_R3ydOIivw8gTY4uwQclUVyz0nhFJa8Mq9PnJV23_9bY54LAv--Rew-aeRSqjOXH_9ZmD3Vijx8cYI8RdL3KCu</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>Jensen, T.K.</creator><creator>Slama, R.</creator><creator>Ducot, B.</creator><creator>Suominen, J.</creator><creator>Cawood, E.H.H.</creator><creator>Andersen, A.G.</creator><creator>Eustache, F.</creator><creator>Irvine, S.</creator><creator>Auger, S.</creator><creator>Jouannet, P.</creator><creator>Vierula, M.</creator><creator>Jørgensen, N.</creator><creator>Toppari, J.</creator><creator>Skakkebaek, N.E.</creator><creator>Keiding, N.</creator><creator>Spira, A.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011201</creationdate><title>Regional differences in waiting time to pregnancy among fertile couples from four European cities</title><author>Jensen, T.K. ; Slama, R. ; Ducot, B. ; Suominen, J. ; Cawood, E.H.H. ; Andersen, A.G. ; Eustache, F. ; Irvine, S. ; Auger, S. ; Jouannet, P. ; Vierula, M. ; Jørgensen, N. ; Toppari, J. ; Skakkebaek, N.E. ; Keiding, N. ; Spira, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c513t-1aa10582cd2751f0a9890d798039540448d35daeddd38fb7e68f4ce1ad9b40d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Biological and medical sciences</topic><topic>Cross-Sectional Studies</topic><topic>Denmark - epidemiology</topic><topic>Educational Status</topic><topic>Environment</topic><topic>environmental health</topic><topic>Female</topic><topic>Fertility</topic><topic>Finland - epidemiology</topic><topic>France - epidemiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Infertility - epidemiology</topic><topic>Infertility - etiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mother. Fetoplacental unit. Mammary gland. Milk</topic><topic>Parity</topic><topic>population surveillance</topic><topic>Pregnancy</topic><topic>pregnancy rate</topic><topic>Pregnancy. Parturition. Lactation</topic><topic>Scotland - epidemiology</topic><topic>Semen - physiology</topic><topic>Sperm Count</topic><topic>Stress, Psychological</topic><topic>Surveys and Questionnaires</topic><topic>Time Factors</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jensen, T.K.</creatorcontrib><creatorcontrib>Slama, R.</creatorcontrib><creatorcontrib>Ducot, B.</creatorcontrib><creatorcontrib>Suominen, J.</creatorcontrib><creatorcontrib>Cawood, E.H.H.</creatorcontrib><creatorcontrib>Andersen, A.G.</creatorcontrib><creatorcontrib>Eustache, F.</creatorcontrib><creatorcontrib>Irvine, S.</creatorcontrib><creatorcontrib>Auger, S.</creatorcontrib><creatorcontrib>Jouannet, P.</creatorcontrib><creatorcontrib>Vierula, M.</creatorcontrib><creatorcontrib>Jørgensen, N.</creatorcontrib><creatorcontrib>Toppari, J.</creatorcontrib><creatorcontrib>Skakkebaek, N.E.</creatorcontrib><creatorcontrib>Keiding, N.</creatorcontrib><creatorcontrib>Spira, A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Human reproduction (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jensen, T.K.</au><au>Slama, R.</au><au>Ducot, B.</au><au>Suominen, J.</au><au>Cawood, E.H.H.</au><au>Andersen, A.G.</au><au>Eustache, F.</au><au>Irvine, S.</au><au>Auger, S.</au><au>Jouannet, P.</au><au>Vierula, M.</au><au>Jørgensen, N.</au><au>Toppari, J.</au><au>Skakkebaek, N.E.</au><au>Keiding, N.</au><au>Spira, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regional differences in waiting time to pregnancy among fertile couples from four European cities</atitle><jtitle>Human reproduction (Oxford)</jtitle><stitle>Hum. Reprod</stitle><addtitle>Hum. Reprod</addtitle><date>2001-12-01</date><risdate>2001</risdate><volume>16</volume><issue>12</issue><spage>2697</spage><epage>2704</epage><pages>2697-2704</pages><issn>0268-1161</issn><eissn>1460-2350</eissn><coden>HUREEE</coden><abstract>BACKGROUND: A previous European study found a longer time to pregnancy (TTP) among fertile women from Paris compared with women from other Western European countries. A co-ordinated, cross-sectional study of pregnant couples from Denmark (Copenhagen), France (Paris), Scotland (Edinburgh) and Finland (Turku) was therefore undertaken to assess differences in waiting TTP among couples from these cities. METHODS: Pregnant women were invited to participate when they showed up for their first antenatal visit in one of the four centres. Inclusion criteria included that their partner was 20–45 years of age and born in the country in which he was currently living and that the pregnancy was achieved without fertility treatment. Both partners filled in a questionnaire and the man underwent a physical examination and delivered a semen sample (Turku: n = 237, Copenhagen: n = 302, Edinburgh: n = 212, Paris: n = 191). RESULTS: French couples had a decreased probability of conception compared with couples from the other three countries, although only after adjustment for confounders. No significant differences between couples from the three other countries were found. CONCLUSION: The observed geographical differences in TTP remain unexplained and were not due to differences in semen quality, but may be caused by varying exposures to environmental factors or psychological distress. In addition, selection bias due to the low participation rates cannot be ruled out. Future studies examining the causes for geographical differences in TTP are needed.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>11726598</pmid><doi>10.1093/humrep/16.12.2697</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Age Factors Biological and medical sciences Cross-Sectional Studies Denmark - epidemiology Educational Status Environment environmental health Female Fertility Finland - epidemiology France - epidemiology Fundamental and applied biological sciences. Psychology Humans Infertility - epidemiology Infertility - etiology Male Middle Aged Mother. Fetoplacental unit. Mammary gland. Milk Parity population surveillance Pregnancy pregnancy rate Pregnancy. Parturition. Lactation Scotland - epidemiology Semen - physiology Sperm Count Stress, Psychological Surveys and Questionnaires Time Factors Vertebrates: reproduction |
title | Regional differences in waiting time to pregnancy among fertile couples from four European cities |
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