Oxidative stress, acute and regular exercise: are they really harmful in the diabetic patient?
Oxidative stress has been involved in the pathogenic process of a variety of diseases including diabetes mellitus. The production of oxidative reactive products has been involved in biochemical changes in bio-molecules that might produce tissue damage directly related to some of the main vascular co...
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| Veröffentlicht in: | Medical hypotheses 2000-07, Vol.55 (1), p.43-46 |
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| container_title | Medical hypotheses |
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| creator | Villa-Caballero, L. Nava-Ocampo, A.A. Frati-Munari, A. Ponce-Monter, H. |
| description | Oxidative stress has been involved in the pathogenic process of a variety of diseases including diabetes mellitus. The production of oxidative reactive products has been involved in biochemical changes in bio-molecules that might produce tissue damage directly related to some of the main vascular complications in the diabetic patient. On the other hand, exercise, paradoxically, is a well-recognized model of oxidative stress and also an important therapeutic tool in diabetes management. Therefore, the relationship between oxidative stress and exercise in diabetic patients implies an interesting biochemical paradox due to some of the negative effects of exercise principally by the increase of oxidative species in plasma. The effect of oxidative stress during an acute exercise and after an aerobic training period on those patients remains unknown and needs to be studied. |
| doi_str_mv | 10.1054/mehy.1999.1000 |
| format | Article |
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The production of oxidative reactive products has been involved in biochemical changes in bio-molecules that might produce tissue damage directly related to some of the main vascular complications in the diabetic patient. On the other hand, exercise, paradoxically, is a well-recognized model of oxidative stress and also an important therapeutic tool in diabetes management. Therefore, the relationship between oxidative stress and exercise in diabetic patients implies an interesting biochemical paradox due to some of the negative effects of exercise principally by the increase of oxidative species in plasma. The effect of oxidative stress during an acute exercise and after an aerobic training period on those patients remains unknown and needs to be studied.</description><subject>Biological and medical sciences</subject><subject>Diabetes Mellitus - blood</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Exercise - physiology</subject><subject>Humans</subject><subject>Management. Various non-drug treatments. 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Impaired glucose tolerance</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Exercise - physiology</topic><topic>Humans</topic><topic>Management. Various non-drug treatments. 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| subjects | Biological and medical sciences Diabetes Mellitus - blood Diabetes Mellitus - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Exercise - physiology Humans Management. Various non-drug treatments. Langerhans islet grafts Medical sciences Models, Biological Oxidative Stress Physical Exertion Reactive Oxygen Species - physiology |
| title | Oxidative stress, acute and regular exercise: are they really harmful in the diabetic patient? |
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