Twelve Years' Experience with National Sharing of HLA-Matched Cadaveric Kidneys for Transplantation

Through an agreement among U.S. transplantation centers, the United Network for Organ Sharing (UNOS) established a program in 1987 to ship kidneys anywhere in the United States to a recipient who had the same HLA-A, B, and DR antigens as the donor. By September 1999, 7614 HLA-matched kidney transpla...

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Veröffentlicht in:The New England journal of medicine 2000-10, Vol.343 (15), p.1078-1084
Hauptverfasser: Takemoto, Steven K, Terasaki, Paul I, Gjertson, David W, Cecka, J. Michael
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container_end_page 1084
container_issue 15
container_start_page 1078
container_title The New England journal of medicine
container_volume 343
creator Takemoto, Steven K
Terasaki, Paul I
Gjertson, David W
Cecka, J. Michael
description Through an agreement among U.S. transplantation centers, the United Network for Organ Sharing (UNOS) established a program in 1987 to ship kidneys anywhere in the United States to a recipient who had the same HLA-A, B, and DR antigens as the donor. By September 1999, 7614 HLA-matched kidney transplantations had been performed. Despite concern about the cost effectiveness and value of this program, the results of the first 1386 HLA-matched transplantations were very promising. 1 Since that time, there have been substantial improvements in immunosuppression protocols, the criteria for the acceptance of organs have been broadened to include older donors, 2 and . . .
doi_str_mv 10.1056/NEJM200010123431504
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine
subjects Actuarial Analysis
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cadaver
Clinical death. Palliative care. Organ gift and preservation
Delivery of Health Care - organization & administration
Graft Rejection
Graft Survival
histocompatibility antigen HLA
Histocompatibility Testing
Ischemia
Kidney Transplantation - immunology
Kidney Transplantation - standards
Kidney Transplantation - statistics & numerical data
Kidneys
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Organ Preservation
Renal failure
Shipments
Survival Analysis
Transplants & implants
United States
title Twelve Years' Experience with National Sharing of HLA-Matched Cadaveric Kidneys for Transplantation
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