Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year
Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function. Methods. During the first year of follow-up after PTMR, 27 pati...
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Veröffentlicht in: | The Annals of thoracic surgery 2000-09, Vol.70 (3), p.1115-1118 |
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container_title | The Annals of thoracic surgery |
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creator | Bortone, Alessandro S D’Agostino, Donato Schena, Stefano Rubini, Giuseppe Viecca, Maurizio Sardaro, Vito Tucci, Antonella de Luca Tupputi Schinosa, Luigi |
description | Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function.
Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.
Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.
Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR. |
doi_str_mv | 10.1016/S0003-4975(00)01791-4 |
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Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.
Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.
Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(00)01791-4</identifier><identifier>PMID: 11016391</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Biological and medical sciences ; Diseases of the cardiovascular system ; Echocardiography ; Female ; Follow-Up Studies ; Humans ; Male ; Medical sciences ; Middle Aged ; Minimally Invasive Surgical Procedures ; Myocardial Revascularization - methods ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Technetium Tc 99m Sestamibi ; Tomography, Emission-Computed, Single-Photon</subject><ispartof>The Annals of thoracic surgery, 2000-09, Vol.70 (3), p.1115-1118</ispartof><rights>2000 The Society of Thoracic Surgeons</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c358t-fca4a8162b162b5284fa52420fab3754c78983c5e09bf9e53e3686a9ed2054be3</citedby><cites>FETCH-LOGICAL-c358t-fca4a8162b162b5284fa52420fab3754c78983c5e09bf9e53e3686a9ed2054be3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003497500017914$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3537,23909,23910,25118,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1518091$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11016391$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bortone, Alessandro S</creatorcontrib><creatorcontrib>D’Agostino, Donato</creatorcontrib><creatorcontrib>Schena, Stefano</creatorcontrib><creatorcontrib>Rubini, Giuseppe</creatorcontrib><creatorcontrib>Viecca, Maurizio</creatorcontrib><creatorcontrib>Sardaro, Vito</creatorcontrib><creatorcontrib>Tucci, Antonella</creatorcontrib><creatorcontrib>de Luca Tupputi Schinosa, Luigi</creatorcontrib><title>Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function.
Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.
Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.
Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Diseases of the cardiovascular system</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Minimally Invasive Surgical Procedures</subject><subject>Myocardial Revascularization - methods</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Technetium Tc 99m Sestamibi</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEuLFDEURoMoTs_oT1CyENFFaZ71mI3IMOrAgAt1HW6lbiCSqrRJqqX99aYfOEsXIYSc77vJIeQFZ-844-37b4wx2aih028Ye8t4N_BGPSIbrrVoWqGHx2TzD7kglzn_rEdRr5-SC36okAPfELxbcknrjEuBQHcQ_ATFx4VGR7eY7FpgwbhmWhIsed5HC2nyFU24g2zXAMn_OSauqYshxN_NuqW1AygUGheke4T0jDxxEDI-P-9X5Men2-83X5r7r5_vbj7eN1bqvjTOgoKet2I8LC165UALJZiDUXZa2a4femk1smF0A2qJsu1bGHASTKsR5RV5ferdpvhrxVzM7LPFEE6fMJ2QjA9KVFCfQJtizgmd2SY_Q9obzsxBjjn6NQd5hjFz9GtUzb08D1jHGaeH1FloBV6dgWoHgqvWrM8PnOY9O2IfThhWGzuPyWTrcbE4-YS2mCn6_7zkL_tQmL8</recordid><startdate>20000901</startdate><enddate>20000901</enddate><creator>Bortone, Alessandro S</creator><creator>D’Agostino, Donato</creator><creator>Schena, Stefano</creator><creator>Rubini, Giuseppe</creator><creator>Viecca, Maurizio</creator><creator>Sardaro, Vito</creator><creator>Tucci, Antonella</creator><creator>de Luca Tupputi Schinosa, Luigi</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000901</creationdate><title>Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year</title><author>Bortone, Alessandro S ; D’Agostino, Donato ; Schena, Stefano ; Rubini, Giuseppe ; Viecca, Maurizio ; Sardaro, Vito ; Tucci, Antonella ; de Luca Tupputi Schinosa, Luigi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c358t-fca4a8162b162b5284fa52420fab3754c78983c5e09bf9e53e3686a9ed2054be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Diseases of the cardiovascular system</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Minimally Invasive Surgical Procedures</topic><topic>Myocardial Revascularization - methods</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Technetium Tc 99m Sestamibi</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bortone, Alessandro S</creatorcontrib><creatorcontrib>D’Agostino, Donato</creatorcontrib><creatorcontrib>Schena, Stefano</creatorcontrib><creatorcontrib>Rubini, Giuseppe</creatorcontrib><creatorcontrib>Viecca, Maurizio</creatorcontrib><creatorcontrib>Sardaro, Vito</creatorcontrib><creatorcontrib>Tucci, Antonella</creatorcontrib><creatorcontrib>de Luca Tupputi Schinosa, Luigi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bortone, Alessandro S</au><au>D’Agostino, Donato</au><au>Schena, Stefano</au><au>Rubini, Giuseppe</au><au>Viecca, Maurizio</au><au>Sardaro, Vito</au><au>Tucci, Antonella</au><au>de Luca Tupputi Schinosa, Luigi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2000-09-01</date><risdate>2000</risdate><volume>70</volume><issue>3</issue><spage>1115</spage><epage>1118</epage><pages>1115-1118</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function.
Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.
Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.
Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11016391</pmid><doi>10.1016/S0003-4975(00)01791-4</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Biological and medical sciences Diseases of the cardiovascular system Echocardiography Female Follow-Up Studies Humans Male Medical sciences Middle Aged Minimally Invasive Surgical Procedures Myocardial Revascularization - methods Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Technetium Tc 99m Sestamibi Tomography, Emission-Computed, Single-Photon |
title | Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year |
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