Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year

Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function. Methods. During the first year of follow-up after PTMR, 27 pati...

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Veröffentlicht in:The Annals of thoracic surgery 2000-09, Vol.70 (3), p.1115-1118
Hauptverfasser: Bortone, Alessandro S, D’Agostino, Donato, Schena, Stefano, Rubini, Giuseppe, Viecca, Maurizio, Sardaro, Vito, Tucci, Antonella, de Luca Tupputi Schinosa, Luigi
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container_end_page 1118
container_issue 3
container_start_page 1115
container_title The Annals of thoracic surgery
container_volume 70
creator Bortone, Alessandro S
D’Agostino, Donato
Schena, Stefano
Rubini, Giuseppe
Viecca, Maurizio
Sardaro, Vito
Tucci, Antonella
de Luca Tupputi Schinosa, Luigi
description Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function. Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole. Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up. Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR.
doi_str_mv 10.1016/S0003-4975(00)01791-4
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Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function. Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole. Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. 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Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function. Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole. Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. 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subjects Aged
Biological and medical sciences
Diseases of the cardiovascular system
Echocardiography
Female
Follow-Up Studies
Humans
Male
Medical sciences
Middle Aged
Minimally Invasive Surgical Procedures
Myocardial Revascularization - methods
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Technetium Tc 99m Sestamibi
Tomography, Emission-Computed, Single-Photon
title Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year
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