Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation
To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema. Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG technique...
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| Veröffentlicht in: | Investigative ophthalmology & visual science 2000-10, Vol.41 (11), p.3655-3664 |
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| container_title | Investigative ophthalmology & visual science |
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| creator | Greenstein, Vivienne C Chen, Haifan Hood, Donald C Holopigian, Karen Seiple, William Carr, Ronald E |
| description | To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema.
Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.
After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.
The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area. |
| format | Article |
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Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.
After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.
The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area.</description><identifier>ISSN: 0146-0404</identifier><identifier>EISSN: 1552-5783</identifier><identifier>PMID: 11006264</identifier><identifier>CODEN: IOVSDA</identifier><language>eng</language><publisher>Rockville, MD: ARVO</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Diabetic Retinopathy - physiopathology ; Diabetic Retinopathy - surgery ; Electroretinography - methods ; Humans ; Laser Coagulation ; Macular Edema - physiopathology ; Macular Edema - surgery ; Medical sciences ; Middle Aged ; Retina - physiology ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the eye and orbit ; Visual Acuity ; Visual Fields</subject><ispartof>Investigative ophthalmology & visual science, 2000-10, Vol.41 (11), p.3655-3664</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=857945$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11006264$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Greenstein, Vivienne C</creatorcontrib><creatorcontrib>Chen, Haifan</creatorcontrib><creatorcontrib>Hood, Donald C</creatorcontrib><creatorcontrib>Holopigian, Karen</creatorcontrib><creatorcontrib>Seiple, William</creatorcontrib><creatorcontrib>Carr, Ronald E</creatorcontrib><title>Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation</title><title>Investigative ophthalmology & visual science</title><addtitle>Invest Ophthalmol Vis Sci</addtitle><description>To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema.
Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.
After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.
The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Diabetic Retinopathy - physiopathology</subject><subject>Diabetic Retinopathy - surgery</subject><subject>Electroretinography - methods</subject><subject>Humans</subject><subject>Laser Coagulation</subject><subject>Macular Edema - physiopathology</subject><subject>Macular Edema - surgery</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retina - physiology</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the eye and orbit</subject><subject>Visual Acuity</subject><subject>Visual Fields</subject><issn>0146-0404</issn><issn>1552-5783</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo90NtKw0AQBuBFFFurryABQa8Ce072UmqrQosieh1mN5tmJYe6mxB8e1davZph-OaHmRM0J0LQVGQ5O0VzTLhMMcd8hi5C-MSYEkLxOZoRgrGkks_R9s0OroMmWY-dGVzfJa5LHhzoODbJFszYgE9WpW0hgWqwPln3JvINhNi_1v3Qmx52Uf0uX6KzCppgr451gT7Wq_flU7p5eXxe3m_SmspsSDMpKsYEtjInXJe50FgqqbhhJhOEKVZaQ3JdYk2lAJlzTXOimaFYKIVtyRbo9pC79_3XaMNQtC4Y2zTQ2X4MRUap4lLRCK-PcNStLYu9dy347-LvARHcHAGEeFfloTMu_LtcZIqLqO4Oqna7enLeFqGFpomhpJimiZMYWDApBPsB1OtwUQ</recordid><startdate>20001001</startdate><enddate>20001001</enddate><creator>Greenstein, Vivienne C</creator><creator>Chen, Haifan</creator><creator>Hood, Donald C</creator><creator>Holopigian, Karen</creator><creator>Seiple, William</creator><creator>Carr, Ronald E</creator><general>ARVO</general><general>Association for Research in Vision and Ophtalmology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20001001</creationdate><title>Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation</title><author>Greenstein, Vivienne C ; Chen, Haifan ; Hood, Donald C ; Holopigian, Karen ; Seiple, William ; Carr, Ronald E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h267t-765f3350e6814bd85b069694c3c751393dec18bd0b265a684b281b3c205990ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Diabetic Retinopathy - physiopathology</topic><topic>Diabetic Retinopathy - surgery</topic><topic>Electroretinography - methods</topic><topic>Humans</topic><topic>Laser Coagulation</topic><topic>Macular Edema - physiopathology</topic><topic>Macular Edema - surgery</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retina - physiology</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the eye and orbit</topic><topic>Visual Acuity</topic><topic>Visual Fields</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Greenstein, Vivienne C</creatorcontrib><creatorcontrib>Chen, Haifan</creatorcontrib><creatorcontrib>Hood, Donald C</creatorcontrib><creatorcontrib>Holopigian, Karen</creatorcontrib><creatorcontrib>Seiple, William</creatorcontrib><creatorcontrib>Carr, Ronald E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Investigative ophthalmology & visual science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Greenstein, Vivienne C</au><au>Chen, Haifan</au><au>Hood, Donald C</au><au>Holopigian, Karen</au><au>Seiple, William</au><au>Carr, Ronald E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation</atitle><jtitle>Investigative ophthalmology & visual science</jtitle><addtitle>Invest Ophthalmol Vis Sci</addtitle><date>2000-10-01</date><risdate>2000</risdate><volume>41</volume><issue>11</issue><spage>3655</spage><epage>3664</epage><pages>3655-3664</pages><issn>0146-0404</issn><eissn>1552-5783</eissn><coden>IOVSDA</coden><abstract>To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema.
Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.
After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.
The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area.</abstract><cop>Rockville, MD</cop><pub>ARVO</pub><pmid>11006264</pmid><tpages>10</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Aged Biological and medical sciences Diabetic Retinopathy - physiopathology Diabetic Retinopathy - surgery Electroretinography - methods Humans Laser Coagulation Macular Edema - physiopathology Macular Edema - surgery Medical sciences Middle Aged Retina - physiology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit Visual Acuity Visual Fields |
| title | Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation |
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