The mechanical environment of the chondrocyte: a biphasic finite element model of cell–matrix interactions in articular cartilage

Mechanical compression of the cartilage extracellular matrix has a significant effect on the metabolic activity of the chondrocytes. However, the relationship between the stress–strain and fluid-flow fields at the macroscopic “tissue” level and those at the microscopic “cellular” level are not fully...

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Veröffentlicht in:	Journal of biomechanics 2000-12, Vol.33 (12), p.1663-1673
Hauptverfasser:	Guilak, Farshid, Mow, Van C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomechanical Phenomena Biomechanics Cartilage, Articular - cytology Cartilage, Articular - physiology Cell mechanics Chondrocytes - physiology Extracellular Matrix - physiology Finite Element Analysis Mechanical properties Mechanical signal transduction Models, Biological Osteoarthritis
Online-Zugang:	Volltext
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