Efficient Delivery of Antennapedia Homeodomain Fused to CTL Epitope with Liposomes into Dendritic Cells Results in the Activation of CD8+ T Cells

The in vivo induction of a CTL response using Antennapedia homeodomain (AntpHD) fused to a poorly immunogenic CTL epitope requires that the Ag is given in presence of SDS, an unacceptable adjuvant for human use. In the present report, we developed a hybrid CTL epitope delivery system consisting of A...

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Veröffentlicht in:The Journal of immunology (1950) 2001-12, Vol.167 (11), p.6462-6470
Hauptverfasser: Chikh, Ghania G, Kong, Spencer, Bally, Marcel B, Meunier, Jean-Claude, Schutze-Redelmeier, Marie-Paule M
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Sprache:eng
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