Transcardiac extraction of circulating endothelin-1 across the failing heart

To determine the transcardiac gradient of plasma endothelin-1 (ET-1) in patients with congestive heart failure (CHF), we measured plasma levels of ET-1 in both the aortic root and the coronary sinus in 14 normal subjects and 79 consecutive patients with CHF. In normal subjects, plasma ET-1 was signi...

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Veröffentlicht in:	The American journal of cardiology 2000-09, Vol.86 (5), p.524-528
Hauptverfasser:	Tsutamoto, Takayoshi, Wada, Atsuyuki, Maeda, Keiko, Mabuchi, Naoko, Hayashi, Masaru, Tsutsui, Takashi, Ohnishi, Masato, Sawaki, Masahide, Fujii, Masanori, Matsumoto, Takehiro, Horie, Hajime, Sugimoto, Yoshihisa, Kinoshita, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - blood Aorta Biological and medical sciences Cardiology. Vascular system Coronary Vessels Endothelin-1 - blood Heart Heart failure Heart Failure - blood Heart Failure - physiopathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Hemodynamics Humans Medical sciences Norepinephrine - blood Peptide Fragments - blood Procollagen - blood Reference Values Ventricular Function, Left
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