Increased plasma homocysteine is an independent predictor of new atherothrombotic brain infarction in older persons
A prospective study investigated the association of plasma homocysteine and other risk factors with the incidence of atherothrombotic brain infarction (ABI) at 31 +/- 9 month follow-up in 153 men and 347 women (mean age 81 +/- 9 years, median age 82). The stepwise Cox regression model showed that si...
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| Veröffentlicht in: | The American journal of cardiology 2000-09, Vol.86 (5), p.585-586 |
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| container_title | The American journal of cardiology |
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| creator | Aronow, Wilbert S Ahn, Chul Gutstein, Hal |
| description | A prospective study investigated the association of plasma homocysteine and other risk factors with the incidence of atherothrombotic brain infarction (ABI) at 31 +/- 9 month follow-up in 153 men and 347 women (mean age 81 +/- 9 years, median age 82). The stepwise Cox regression model showed that significant independent predictors of new ABI in older persons were age (risk ratio 1.060 for each 1-year increase of age), plasma homocysteine (risk ratio 1.079 for each 1 micromol/L increase), prior ABI infarction (risk ratio 3.282), current cigarette smoking (risk ratio 2.687), hypertension (risk ratio 2.965), and diabetes mellitus (risk ratio 2.015). |
| doi_str_mv | 10.1016/S0002-9149(00)01025-0 |
| format | Article |
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Ahn, Chul ; Gutstein, Hal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-7dd702d340c7c3e286e5713331338d324568e88881e6d721b0cc94f5eb58b0253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Brain</topic><topic>Cardiovascular disease</topic><topic>Cerebral Infarction - etiology</topic><topic>Diabetes Complications</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Hyperhomocysteinemia - complications</topic><topic>Hypertension - complications</topic><topic>Intracranial Thrombosis - etiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Older people</topic><topic>Risk Factors</topic><topic>Smoking - adverse effects</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aronow, Wilbert S</creatorcontrib><creatorcontrib>Ahn, Chul</creatorcontrib><creatorcontrib>Gutstein, Hal</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aronow, Wilbert S</au><au>Ahn, Chul</au><au>Gutstein, Hal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased plasma homocysteine is an independent predictor of new atherothrombotic brain infarction in older persons</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2000-09-01</date><risdate>2000</risdate><volume>86</volume><issue>5</issue><spage>585</spage><epage>586</epage><pages>585-586</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>A prospective study investigated the association of plasma homocysteine and other risk factors with the incidence of atherothrombotic brain infarction (ABI) at 31 +/- 9 month follow-up in 153 men and 347 women (mean age 81 +/- 9 years, median age 82). 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| ispartof | The American journal of cardiology, 2000-09, Vol.86 (5), p.585-586 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Aged, 80 and over Biological and medical sciences Brain Cardiovascular disease Cerebral Infarction - etiology Diabetes Complications Female Follow-Up Studies Health risk assessment Humans Hyperhomocysteinemia - complications Hypertension - complications Intracranial Thrombosis - etiology Male Medical sciences Middle Aged Neurology Older people Risk Factors Smoking - adverse effects Vascular diseases and vascular malformations of the nervous system |
| title | Increased plasma homocysteine is an independent predictor of new atherothrombotic brain infarction in older persons |
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