Tiospirone and the Reinforcing Effects of Cocaine in the Conditioned Place Preference Paradigm in Rats

Tiospirone (TSP) is an atypical antipsychotic drug. It has 5HT‐2 antagonistic properties as well as affinity for D2, 5HT‐1a, 5HT‐6 and sigma receptors. Behavioural studies in our laboratory, which used a 24 h free access to food and fluids paradigm, showed a decreased alcohol and increased food inta...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2000-08, Vol.52 (8), p.977-981
Hauptverfasser:	AROLFO, MARIA PIA, MCMILLEN, BRIAN A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking Analysis of Variance Animals Behavior, Animal - drug effects Biological and medical sciences Cocaine - antagonists & inhibitors Dose-Response Relationship, Drug Drug addictions Eating - drug effects Male Medical sciences Psychotropic Drugs - administration & dosage Psychotropic Drugs - pharmacology Rats Rats, Sprague-Dawley Spiro Compounds - administration & dosage Spiro Compounds - pharmacology Toxicology
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