Antioxidant and Antiprotease Status in Peripheral Blood and BAL Fluid After Cardiopulmonary Bypass

Cardiopulmonary bypass (CPB) triggers systemic inflammation. Recent evidence suggests that metabolic and oxygenation management can affect the outcome of patients after cardiac surgery. We investigated the influence of oxidant/antioxidant and protease/antiprotease imbalance during the course of syst...

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Veröffentlicht in:	Chest 2001-11, Vol.120 (5), p.1599-1608
Hauptverfasser:	Frass, Oliver M., Bu¨hling, Frank, Ta¨ger, Michael, Frass, Heidrun, Ansorge, Siegfried, Huth, Christof, Welte, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha 1-Antitrypsin - metabolism Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antioxidants Antioxidants - metabolism antiproteases BAL Biological and medical sciences Blood Cell Count blood glucose Blood Glucose - analysis Bronchoalveolar Lavage Fluid - chemistry Cardiac Surgical Procedures cardiopulmonary bypass Cardiopulmonary Bypass - adverse effects Cathepsins - blood elastase Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Free radicals Glucose glutathione Granulocytes Heart surgery Humans Inflammation Intensive care medicine intracellular thiol Leukocytes Lymphocytes Male Medical sciences Metabolism Middle Aged Neutrophils Oxygen - blood oxygenation Pancreatic Elastase - metabolism Patients Permeability Protease Inhibitors - metabolism Proteinase Inhibitory Proteins, Secretory Proteins Proteins - metabolism Secretory Leukocyte Peptidase Inhibitor Sulfhydryl Compounds - blood systemic inflammation Systemic Inflammatory Response Syndrome - etiology Systemic Inflammatory Response Syndrome - metabolism
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