Functional Roles of the Two Domains of Phosducin and Phosducin-like Protein

Phosducin and phosducin-like protein regulate G protein signaling pathways by binding the βγ subunit complex (Gβγ) and blocking Gβγ association with Gα subunits, effector enzymes, or membranes. Both proteins are composed of two structurally independent domains, each constituting approximately half o...

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