Influence of Deep Hypothermia on the Tolerance of the Isolated Cardiomyocyte to Ischemia–Reperfusion

The influence of deep hypothermia (4°C) during a substrate-free, hypoxia–reoxygenation treatment was investigated on cardiomyocytes (CM) prepared from newborn rat heart in culture in an in vitro, substrate-free model of ischemia–reperfusion. The transmembranous potentials were recorded with standard...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2001-11, Vol.33 (11), p.1973-1988
Hauptverfasser:	Bes, Sandrine, Roussel, Pascal, Laubriet, Aline, Vandroux, David, Tissier, Cindy, Rochette, Luc, Athias, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cardiomyocytes Cells, Cultured Cellular contractions Cellular culture Deep hypothermia Electrophysiology Heat-Shock Proteins - metabolism HSP70 HSP70 Heat-Shock Proteins - metabolism Hypothermia Ischemia - metabolism Messenger RNA Myocardial Ischemia - prevention & control Myocardial Reperfusion Injury - prevention & control Myocardium - cytology Myocardium - metabolism Rat Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction RNA - metabolism RNA, Messenger - metabolism Simulated ischemia–reperfusion Temperature Time Factors
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