Preclinical Pharmacology of GAR-936, a Novel Glycylcycline Antibacterial Agent

GAR‐936 is an analog of minocycline, a semisynthetic derivative of tetracycline. It has broad‐spectrum antibacterial activity in vitro and in vivo. The new class of tetracyclines to which GAR‐936 belongs is named the glycylcyclines. Tetracyclines act by inhibiting protein translation in bacteria, pr...

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Veröffentlicht in:	Pharmacotherapy 2000-09, Vol.20 (9P2), p.219S-223S
1. Verfasser:	Projan, Steven J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Medical sciences Microbial Sensitivity Tests Minocycline - analogs & derivatives Minocycline - pharmacology Pharmacology. Drug treatments Tetracycline Resistance
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