The SCF ubiquitin ligase protein Slimb regulates centrosome duplication in Drosophila

The duplication of the centrosome is a key event in the cell-division cycle. Although defects in centrosome duplication are thought to contribute to genomic instability [1–3] and are a hallmark of certain transformed cells and human cancer [4–6], the mechanism responsible for centrosome duplication...

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