An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard
In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with Francisella tularensis infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely tha...
Gespeichert in:
Veröffentlicht in: | The New England journal of medicine 2001-11, Vol.345 (22), p.1601-1606 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1606 |
---|---|
container_issue | 22 |
container_start_page | 1601 |
container_title | The New England journal of medicine |
container_volume | 345 |
creator | Feldman, Katherine A Enscore, Russell E Lathrop, Sarah L Matyas, Bela T McGuill, Michael Schriefer, Martin E Stiles-Enos, Donna Dennis, David T Petersen, Lyle R Hayes, Edward B |
description | In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with
Francisella tularensis
infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness.
Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus
Francisella tularensis
. The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented.
After an incubation period of 3 to 5 days (range, 1 to 21), infection with
F. tularensis
can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. Primary pneumonic tularemia results . . . |
doi_str_mv | 10.1056/NEJMoa011374 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72279208</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72279208</sourcerecordid><originalsourceid>FETCH-LOGICAL-c671t-793121e24d1fb1b8b33b93d3160a4ac74a8a23d0ebef7a8c0bbcc1adbbea7b9e3</originalsourceid><addsrcrecordid>eNqF0M9LwzAUwPEgis7pzbMU8cfFal6SNs1JZPiTTT1Mr-UlTbGzTTVZD_73dmygiGAuuXx4L_kSsgf0DGiSnj9c3U9apABcijUygITzWAiarpMBpSyLhVR8i2yHMKP9AaE2yRaATGRC0wG5uHTRYzfX3uJb1JbRk68a9J_Rk7Nd07rKRNOuRm-bCqPWRRP081c8CdFL5ewn-mKHbJRYB7u7uofk-fpqOrqNx483d6PLcWxSCfO4fwMwsEwUUGrQmeZcK15wSCkKNFJghowX1GpbSswM1doYwEJri1Iry4fkeDn33bcfnQ3zvKmCsXWNzrZdyCVjUjGa_QshY3yRoYcHv-Cs7bzrP5EzxhVXqVI9Ol0i49sQvC3z92WgHGi-yJ__zN_z_dXMTje2-Mar3j04WgEMBuvSozNV-HYCIEkz3rvDpWuakDs7a_7e9wUFJ5br</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>223939699</pqid></control><display><type>article</type><title>An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>New England Journal of Medicine</source><creator>Feldman, Katherine A ; Enscore, Russell E ; Lathrop, Sarah L ; Matyas, Bela T ; McGuill, Michael ; Schriefer, Martin E ; Stiles-Enos, Donna ; Dennis, David T ; Petersen, Lyle R ; Hayes, Edward B</creator><creatorcontrib>Feldman, Katherine A ; Enscore, Russell E ; Lathrop, Sarah L ; Matyas, Bela T ; McGuill, Michael ; Schriefer, Martin E ; Stiles-Enos, Donna ; Dennis, David T ; Petersen, Lyle R ; Hayes, Edward B</creatorcontrib><description>In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with
Francisella tularensis
infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness.
Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus
Francisella tularensis
. The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented.
After an incubation period of 3 to 5 days (range, 1 to 21), infection with
F. tularensis
can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. Primary pneumonic tularemia results . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa011374</identifier><identifier>PMID: 11757506</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Adolescent ; Adult ; Animals ; Antibodies, Bacterial - blood ; Bacterial diseases ; Bacterial diseases of the respiratory system ; Biological and medical sciences ; Case-Control Studies ; Disease Outbreaks ; Female ; Francisella tularensis ; Francisella tularensis - immunology ; Francisella tularensis - isolation & purification ; General aspects ; Human bacterial diseases ; Humans ; Infections ; Infectious diseases ; lawn mowing ; Male ; Massachusetts - epidemiology ; Medical sciences ; Mephitidae - microbiology ; Mortality ; outbreaks ; Planification. Prevention (methods). Intervention. Evaluation ; Pneumonia, Bacterial - epidemiology ; pneumonic tularemia ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Rats - microbiology ; Risk Factors ; Tularemia ; Tularemia - epidemiology</subject><ispartof>The New England journal of medicine, 2001-11, Vol.345 (22), p.1601-1606</ispartof><rights>Copyright © 2001 Massachusetts Medical Society. All rights reserved.</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c671t-793121e24d1fb1b8b33b93d3160a4ac74a8a23d0ebef7a8c0bbcc1adbbea7b9e3</citedby><cites>FETCH-LOGICAL-c671t-793121e24d1fb1b8b33b93d3160a4ac74a8a23d0ebef7a8c0bbcc1adbbea7b9e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa011374$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa011374$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14115683$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11757506$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Feldman, Katherine A</creatorcontrib><creatorcontrib>Enscore, Russell E</creatorcontrib><creatorcontrib>Lathrop, Sarah L</creatorcontrib><creatorcontrib>Matyas, Bela T</creatorcontrib><creatorcontrib>McGuill, Michael</creatorcontrib><creatorcontrib>Schriefer, Martin E</creatorcontrib><creatorcontrib>Stiles-Enos, Donna</creatorcontrib><creatorcontrib>Dennis, David T</creatorcontrib><creatorcontrib>Petersen, Lyle R</creatorcontrib><creatorcontrib>Hayes, Edward B</creatorcontrib><title>An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with
Francisella tularensis
infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness.
Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus
Francisella tularensis
. The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented.
After an incubation period of 3 to 5 days (range, 1 to 21), infection with
F. tularensis
can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. Primary pneumonic tularemia results . . .</description><subject>Adolescent</subject><subject>Adult</subject><subject>Animals</subject><subject>Antibodies, Bacterial - blood</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the respiratory system</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Disease Outbreaks</subject><subject>Female</subject><subject>Francisella tularensis</subject><subject>Francisella tularensis - immunology</subject><subject>Francisella tularensis - isolation & purification</subject><subject>General aspects</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>lawn mowing</subject><subject>Male</subject><subject>Massachusetts - epidemiology</subject><subject>Medical sciences</subject><subject>Mephitidae - microbiology</subject><subject>Mortality</subject><subject>outbreaks</subject><subject>Planification. Prevention (methods). Intervention. Evaluation</subject><subject>Pneumonia, Bacterial - epidemiology</subject><subject>pneumonic tularemia</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Rats - microbiology</subject><subject>Risk Factors</subject><subject>Tularemia</subject><subject>Tularemia - epidemiology</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0M9LwzAUwPEgis7pzbMU8cfFal6SNs1JZPiTTT1Mr-UlTbGzTTVZD_73dmygiGAuuXx4L_kSsgf0DGiSnj9c3U9apABcijUygITzWAiarpMBpSyLhVR8i2yHMKP9AaE2yRaATGRC0wG5uHTRYzfX3uJb1JbRk68a9J_Rk7Nd07rKRNOuRm-bCqPWRRP081c8CdFL5ewn-mKHbJRYB7u7uofk-fpqOrqNx483d6PLcWxSCfO4fwMwsEwUUGrQmeZcK15wSCkKNFJghowX1GpbSswM1doYwEJri1Iry4fkeDn33bcfnQ3zvKmCsXWNzrZdyCVjUjGa_QshY3yRoYcHv-Cs7bzrP5EzxhVXqVI9Ol0i49sQvC3z92WgHGi-yJ__zN_z_dXMTje2-Mar3j04WgEMBuvSozNV-HYCIEkz3rvDpWuakDs7a_7e9wUFJ5br</recordid><startdate>20011129</startdate><enddate>20011129</enddate><creator>Feldman, Katherine A</creator><creator>Enscore, Russell E</creator><creator>Lathrop, Sarah L</creator><creator>Matyas, Bela T</creator><creator>McGuill, Michael</creator><creator>Schriefer, Martin E</creator><creator>Stiles-Enos, Donna</creator><creator>Dennis, David T</creator><creator>Petersen, Lyle R</creator><creator>Hayes, Edward B</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7QL</scope><scope>7T2</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>20011129</creationdate><title>An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard</title><author>Feldman, Katherine A ; Enscore, Russell E ; Lathrop, Sarah L ; Matyas, Bela T ; McGuill, Michael ; Schriefer, Martin E ; Stiles-Enos, Donna ; Dennis, David T ; Petersen, Lyle R ; Hayes, Edward B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c671t-793121e24d1fb1b8b33b93d3160a4ac74a8a23d0ebef7a8c0bbcc1adbbea7b9e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Animals</topic><topic>Antibodies, Bacterial - blood</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the respiratory system</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Disease Outbreaks</topic><topic>Female</topic><topic>Francisella tularensis</topic><topic>Francisella tularensis - immunology</topic><topic>Francisella tularensis - isolation & purification</topic><topic>General aspects</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>lawn mowing</topic><topic>Male</topic><topic>Massachusetts - epidemiology</topic><topic>Medical sciences</topic><topic>Mephitidae - microbiology</topic><topic>Mortality</topic><topic>outbreaks</topic><topic>Planification. Prevention (methods). Intervention. Evaluation</topic><topic>Pneumonia, Bacterial - epidemiology</topic><topic>pneumonic tularemia</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Rats - microbiology</topic><topic>Risk Factors</topic><topic>Tularemia</topic><topic>Tularemia - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Feldman, Katherine A</creatorcontrib><creatorcontrib>Enscore, Russell E</creatorcontrib><creatorcontrib>Lathrop, Sarah L</creatorcontrib><creatorcontrib>Matyas, Bela T</creatorcontrib><creatorcontrib>McGuill, Michael</creatorcontrib><creatorcontrib>Schriefer, Martin E</creatorcontrib><creatorcontrib>Stiles-Enos, Donna</creatorcontrib><creatorcontrib>Dennis, David T</creatorcontrib><creatorcontrib>Petersen, Lyle R</creatorcontrib><creatorcontrib>Hayes, Edward B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Feldman, Katherine A</au><au>Enscore, Russell E</au><au>Lathrop, Sarah L</au><au>Matyas, Bela T</au><au>McGuill, Michael</au><au>Schriefer, Martin E</au><au>Stiles-Enos, Donna</au><au>Dennis, David T</au><au>Petersen, Lyle R</au><au>Hayes, Edward B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2001-11-29</date><risdate>2001</risdate><volume>345</volume><issue>22</issue><spage>1601</spage><epage>1606</epage><pages>1601-1606</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with
Francisella tularensis
infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness.
Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus
Francisella tularensis
. The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented.
After an incubation period of 3 to 5 days (range, 1 to 21), infection with
F. tularensis
can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. Primary pneumonic tularemia results . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>11757506</pmid><doi>10.1056/NEJMoa011374</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0028-4793 |
ispartof | The New England journal of medicine, 2001-11, Vol.345 (22), p.1601-1606 |
issn | 0028-4793 1533-4406 |
language | eng |
recordid | cdi_proquest_miscellaneous_72279208 |
source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Adolescent Adult Animals Antibodies, Bacterial - blood Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Case-Control Studies Disease Outbreaks Female Francisella tularensis Francisella tularensis - immunology Francisella tularensis - isolation & purification General aspects Human bacterial diseases Humans Infections Infectious diseases lawn mowing Male Massachusetts - epidemiology Medical sciences Mephitidae - microbiology Mortality outbreaks Planification. Prevention (methods). Intervention. Evaluation Pneumonia, Bacterial - epidemiology pneumonic tularemia Public health. Hygiene Public health. Hygiene-occupational medicine Rats - microbiology Risk Factors Tularemia Tularemia - epidemiology |
title | An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T14%3A48%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20Outbreak%20of%20Primary%20Pneumonic%20Tularemia%20on%20Martha's%20Vineyard&rft.jtitle=The%20New%20England%20journal%20of%20medicine&rft.au=Feldman,%20Katherine%20A&rft.date=2001-11-29&rft.volume=345&rft.issue=22&rft.spage=1601&rft.epage=1606&rft.pages=1601-1606&rft.issn=0028-4793&rft.eissn=1533-4406&rft.coden=NEJMAG&rft_id=info:doi/10.1056/NEJMoa011374&rft_dat=%3Cproquest_cross%3E72279208%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=223939699&rft_id=info:pmid/11757506&rfr_iscdi=true |