An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard

In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with Francisella tularensis infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely tha...

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Veröffentlicht in:The New England journal of medicine 2001-11, Vol.345 (22), p.1601-1606
Hauptverfasser: Feldman, Katherine A, Enscore, Russell E, Lathrop, Sarah L, Matyas, Bela T, McGuill, Michael, Schriefer, Martin E, Stiles-Enos, Donna, Dennis, David T, Petersen, Lyle R, Hayes, Edward B
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container_issue 22
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container_title The New England journal of medicine
container_volume 345
creator Feldman, Katherine A
Enscore, Russell E
Lathrop, Sarah L
Matyas, Bela T
McGuill, Michael
Schriefer, Martin E
Stiles-Enos, Donna
Dennis, David T
Petersen, Lyle R
Hayes, Edward B
description In the summer of 2000, there was an outbreak of tularemia on the island of Martha's Vineyard in Massachusetts. This case–control study identified 15 patients with Francisella tularensis infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness. Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus Francisella tularensis . The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented. After an incubation period of 3 to 5 days (range, 1 to 21), infection with F. tularensis can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. Primary pneumonic tularemia results . . .
doi_str_mv 10.1056/NEJMoa011374
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This case–control study identified 15 patients with Francisella tularensis infection, including 11 with primary pneumonic tularemia. One patient died. The patients were more likely than controls to have used a lawn mower or brush cutter in the two weeks before the illness. Tularemia is a bacterial zoonosis caused by the small, gram-negative coccobacillus Francisella tularensis . The organism may be found in contaminated water or soil, infected ticks, wild and domestic animals, and decaying animal carcasses. Mammals can acquire the infection through arthropod bites, direct contact with infected tissues, inhalation, or ingestion; person-to-person transmission has not been documented. After an incubation period of 3 to 5 days (range, 1 to 21), infection with F. tularensis can result in various clinical presentations, depending on the route of inoculation, the dose of the inoculum, and the virulence of the organism. 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subjects Adolescent
Adult
Animals
Antibodies, Bacterial - blood
Bacterial diseases
Bacterial diseases of the respiratory system
Biological and medical sciences
Case-Control Studies
Disease Outbreaks
Female
Francisella tularensis
Francisella tularensis - immunology
Francisella tularensis - isolation & purification
General aspects
Human bacterial diseases
Humans
Infections
Infectious diseases
lawn mowing
Male
Massachusetts - epidemiology
Medical sciences
Mephitidae - microbiology
Mortality
outbreaks
Planification. Prevention (methods). Intervention. Evaluation
Pneumonia, Bacterial - epidemiology
pneumonic tularemia
Public health. Hygiene
Public health. Hygiene-occupational medicine
Rats - microbiology
Risk Factors
Tularemia
Tularemia - epidemiology
title An Outbreak of Primary Pneumonic Tularemia on Martha's Vineyard
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