The Role of PTF1-P48 in Pancreatic Acinar Gene Expression

The 100-base pair ELA1transcriptional enhancer drives high level transcription to pancreatic acinar cells of transgenic mice and in transfected pancreatic acinar cells in culture. The A element within the enhancer is the sole positively acting element for acinar specificity. We show that the acinar...

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Veröffentlicht in:	The Journal of biological chemistry 2001-11, Vol.276 (47), p.44018-44026
Hauptverfasser:	Rose, Scott D., Swift, Galvin H., Peyton, Michael J., Hammer, Robert E., MacDonald, Raymond J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Basic Helix-Loop-Helix Transcription Factors DNA Primers DNA-Binding Proteins - physiology Gene Expression Regulation - physiology HEB protein HeLa Cells Humans Mice Molecular Sequence Data Pancreas - cytology Pancreas - metabolism PTF1-P48 protein Rats Rats, Sprague-Dawley Transcription Factors - physiology Transcription, Genetic - physiology
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