Amplified in situ hybridization with peptide nucleic acid probes for differentiation of Mycobacterium tuberculosis complex and nontuberculous Mycobacterium species on formalin-fixed, paraffin-embedded archival biopsy and autopsy samples

The aim of this study was to evaluate sensitivity and specificity of in situ hybridization (ISH) using peptide nucleic acid (PNA) probes and tyramide-based amplification for the differentiation between Mycobacterium tuberculosis (MTB) and mycobacteria other than tuberculosis (MOTT) on formalin-fixed...

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Veröffentlicht in:	American journal of clinical pathology 2001-11, Vol.116 (5), p.770-775
Hauptverfasser:	ZERBI, Pietro, SCHØNAU, Andreas, BONETTO, Sara, GORI, Andrea, COSTANZI, Giulio, DUCA, Piergiorgio, VAGO, Luca
Format:	Artikel
Sprache:	eng
Schlagworte:	Autopsy Biological and medical sciences Biopsy Formaldehyde In Situ Hybridization - methods Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous. Technology Mycobacterium Infections - diagnosis Mycobacterium Infections - microbiology Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - growth & development Mycobacterium tuberculosis - isolation & purification Nucleic Acid Probes - genetics Paraffin Embedding Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Peptide Nucleic Acids Sensitivity and Specificity Tissue Fixation
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