The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC

The neuropeptide head activator stimulates cell proliferation of neuronal precursor and neuroendocrine cells. The mitogenic signaling cascade requires Ca(2+) influx for which, as we show in this paper, the growth-factor-regulated Ca(2+)-permeable cation channel, GRC, is responsible. GRC is a member...

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Veröffentlicht in:	Journal of cell science 2001-10, Vol.114 (Pt 20), p.3599-3606
Hauptverfasser:	Boels, K, Glassmeier, G, Herrmann, D, Riedel, I B, Hampe, W, Kojima, I, Schwarz, J R, Schaller, H C
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstadienes - pharmacology Animals Benzylamines - pharmacology Calcium - metabolism Calcium Channel Blockers - pharmacology Calcium Channels - genetics Calcium Channels - metabolism Cell Membrane CHO Cells COS Cells Cricetinae Enzyme Inhibitors - pharmacology Humans Imidazoles - pharmacology Microscopy, Fluorescence Models, Biological Neurons - cytology Neurons - drug effects Neurons - physiology Neuropeptides - pharmacology Patch-Clamp Techniques Pertussis Toxin Protein Transport Purines - pharmacology Pyrrolidonecarboxylic Acid - analogs & derivatives Recombinant Fusion Proteins - metabolism Roscovitine Signal Transduction Sulfonamides - pharmacology TRPV Cation Channels Virulence Factors, Bordetella - pharmacology Wortmannin
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