Depression and nicotine: preclinical and clinical evidence for common mechanisms

Updated findings on the relationship between nicotine and depression are presented. Clinical and preclinical research on nicotine use and depression suggests that nicotine may have some properties in common with antidepressants. Updated findings involve the comorbidity of smoking and major depressiv...

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Veröffentlicht in:Current psychiatry reports 2001-12, Vol.3 (6), p.470-474
Hauptverfasser: Laje, R P, Berman, J A, Glassman, A H
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Berman, J A
Glassman, A H
description Updated findings on the relationship between nicotine and depression are presented. Clinical and preclinical research on nicotine use and depression suggests that nicotine may have some properties in common with antidepressants. Updated findings involve the comorbidity of smoking and major depressive disorder (MDD), the influence of depression during withdrawal on failure to quit smoking, the course of MDD without nicotine and the neurobiology of smoking and depression.
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subjects Antidepressive Agents - therapeutic use
Comorbidity
Depressive Disorder, Major - drug therapy
Depressive Disorder, Major - epidemiology
Humans
Mental depression
Neurosciences
Nicotine
Nicotine - pharmacology
Nicotine - therapeutic use
Psychiatry
Receptors, Cholinergic - drug effects
Receptors, Nicotinic - drug effects
Smoking
Smoking - epidemiology
Smoking Cessation
title Depression and nicotine: preclinical and clinical evidence for common mechanisms
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