Effects of human recombinant luteinizing hormone and follicle-stimulating hormone in patients with acquired hypogonadotropic hypogonadism : Study of Sertoli and Leydig cell secretions and interactions

Experimental data suggest that FSH-stimulated Sertoli cells can enhance LH-induced Leydig cell testosterone (T) production. The function of Leydig and Sertoli cells can be selectively studied by using recombinant human LH (rhLH) and recombinant human FSH (rhFSH) in patients with complete gonadotropi...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2000-09, Vol.85 (9), p.3239-3244
Hauptverfasser:	YOUNG, Jacques, COUZINET, Beatrice, CHANSON, Philippe, BRAILLY, Sylvie, LOUMAYE, Ernest, SCHAISON, Gilbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Estradiol - blood Follicle Stimulating Hormone - blood Follicle Stimulating Hormone - therapeutic use Genital system. Reproduction Gonadotropins - deficiency Humans Hypogonadism - drug therapy Hypogonadism - metabolism Inhibins - blood Leydig Cells - drug effects Leydig Cells - metabolism Leydig Cells - pathology Luteinizing Hormone - blood Luteinizing Hormone - therapeutic use Male Medical sciences Pharmacology. Drug treatments Recombinant Proteins - therapeutic use Sertoli Cells - drug effects Sertoli Cells - metabolism Sertoli Cells - pathology Testosterone - blood Time Factors
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