Naringin Has an Antiatherogenic Effect With the Inhibition of Intercellular Adhesion Molecule-1 in Hypercholesterolemic Rabbits

Naringin, a bioflavonoid found in citrus fruit peel, is known to have an antioxidative effect, but its effect on atherosclerosis has not been studied. This study evaluated the effect of naringin on blood lipid levels and aortic fatty streaks, and its action mechanism in hypercholesterolemic rabbits....

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2001-12, Vol.38 (6), p.947-955
Hauptverfasser:	Choe, Seong-Choon, Kim, Hyo-Soo, Jeong, Tae-Sook, Bok, Song-Hae, Park, Young-Bae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - pharmacology Anticholesteremic Agents - therapeutic use Aorta, Thoracic - metabolism Aorta, Thoracic - pathology Arteriosclerosis - blood Arteriosclerosis - pathology Arteriosclerosis - prevention & control Biological and medical sciences Cardiovascular system Cholesterol - blood Cholesterol, HDL - blood Diet, Atherogenic Flavanones Flavonoids - pharmacology Flavonoids - therapeutic use Foam Cells General pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hypercholesterolemia - drug therapy Hypercholesterolemia - metabolism Hypercholesterolemia - pathology Immunohistochemistry Intercellular Adhesion Molecule-1 - immunology Intercellular Adhesion Molecule-1 - metabolism Liver - drug effects Liver - pathology Lovastatin - pharmacology Male Medical sciences Miscellaneous Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Rabbits Time Factors Triglycerides - blood
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