Options for Tissue Engineering to Address Challenges of the Aging Skeleton
There will be more than 52 million Americans over the age of 65 by the year 2020 (U.S. Census Bureau). Regenerating form and function to bone defects in an elderly, osteoporotic population of this magnitude will be a daunting challenge. Tissue engineering options must be considered to answer this ch...
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Veröffentlicht in: | Tissue engineering 2000-08, Vol.6 (4), p.341-350 |
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creator | Hollinger, Jeffrey O. Winn, Shelley Bonadio, Jeffrey |
description | There will be more than 52 million Americans over the age of 65 by the year 2020 (U.S. Census Bureau). Regenerating form and function to bone defects in an elderly, osteoporotic population of this magnitude
will be a daunting challenge. Tissue engineering options must be considered to answer this challenge. Options can include gene transfer technology, stem cell therapy, and recombinant signaling molecules.
An additional component will be a carrier that localizes, protects, predictably releases cues and cells, as well as establishes an environment for restoring osseous form and function. The purposes of this
article are to present an overview of the bone regenerating decrement affecting osteoporotic, elderly patients and to highlight some tissue engineering options that could offset this decrement. |
doi_str_mv | 10.1089/107632700418065 |
format | Article |
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An additional component will be a carrier that localizes, protects, predictably releases cues and cells, as well as establishes an environment for restoring osseous form and function. The purposes of this
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An additional component will be a carrier that localizes, protects, predictably releases cues and cells, as well as establishes an environment for restoring osseous form and function. The purposes of this
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Regenerating form and function to bone defects in an elderly, osteoporotic population of this magnitude
will be a daunting challenge. Tissue engineering options must be considered to answer this challenge. Options can include gene transfer technology, stem cell therapy, and recombinant signaling molecules.
An additional component will be a carrier that localizes, protects, predictably releases cues and cells, as well as establishes an environment for restoring osseous form and function. The purposes of this
article are to present an overview of the bone regenerating decrement affecting osteoporotic, elderly patients and to highlight some tissue engineering options that could offset this decrement.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc</pub><pmid>10992431</pmid><doi>10.1089/107632700418065</doi><tpages>10</tpages></addata></record> |
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subjects | Aged Aging - physiology Animals Biomedical Engineering Bone Regeneration Gene Transfer Techniques Humans Osteoporosis - physiopathology Osteoporosis - therapy Portland Bone Symposium United States |
title | Options for Tissue Engineering to Address Challenges of the Aging Skeleton |
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