Only one nemo-like kinase gene homologue in invertebrate and mammalian genomes

The nemo-like kinase (Nlk) connects the MAP kinase and Wnt signalling pathways. We have found that invertebrate (Caenorhabditis elegans, Drosophila melanogaster) and mammalian genomes ( Mus musculus and Homo sapiens) each contain only a single functional Nlk gene. The mouse genome also harbours a tr...

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Veröffentlicht in:	Gene 2001-10, Vol.278 (1), p.161-165
Hauptverfasser:	Kortenjann, Monika, Wehrle, Christian, Nehls, Michael C., Boehm, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals b-catenin Blotting, Southern Caenorhabditis elegans Caenorhabditis elegans - genetics chromosome 2 DNA - genetics Drosophila melanogaster Drosophila melanogaster - genetics Genome Genomes Humans LEF protein Mice Mitogen-Activated Protein Kinases - genetics Molecular Sequence Data Nemo-like kinase Nlk gene Protein Isoforms - genetics Pseudogenes - genetics Sequence Alignment Sequence Homology, Amino Acid TCF protein Wnt protein
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