Coronary microvascular endothelial cells cosecrete angiotensin II and endothelin-1 via a regulated pathway

1 Division of Endocrinology-Hypertension and 2 Division of Cardiology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachuesetts 02115 Although endothelial cells produce angiotensin II (ANG II) and endothelin-1 (ET-1), it is not clear whether a si...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2000-09, Vol.279 (3), p.H1087-H1096
Hauptverfasser:	Kusaka, Yasuko, Kelly, Ralph A, Williams, Gordon H, Kifor, Imre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - pharmacology Angiotensin II - metabolism Angiotensin II - secretion Animals Antibody Specificity Cadmium - pharmacology Cell Size Cells, Cultured Coronary Vessels - cytology Coronary Vessels - metabolism Cycloheximide - pharmacology Endothelin-1 - metabolism Endothelin-1 - secretion Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Enzyme Inhibitors - pharmacology Immunoblotting Immunohistochemistry Male Microcirculation - cytology Microcirculation - metabolism Nitric Oxide Donors - pharmacology Potassium - pharmacology Protein Synthesis Inhibitors - pharmacology Rats Rats, Sprague-Dawley Signal Transduction - drug effects Vasodilator Agents - pharmacology
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