Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease
The atrial natriuretic peptide (ANP) gene may underlie stroke susceptibility and sensitivity to cerebral ischemia in an animal model of stroke. The authors investigate its role in humans by genotyping a polymorphism (G664A) in 436 patients with ischemic cerebrovascular disease and 295 community cont...
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| Veröffentlicht in: | Neurology 2001-11, Vol.57 (9), p.1726-1728 |
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| container_title | Neurology |
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| creator | HASSAN, A ALI, N DONG, Y CARTER, N. D MARKUS, H. S |
| description | The atrial natriuretic peptide (ANP) gene may underlie stroke susceptibility and sensitivity to cerebral ischemia in an animal model of stroke. The authors investigate its role in humans by genotyping a polymorphism (G664A) in 436 patients with ischemic cerebrovascular disease and 295 community control subjects. The frequency of this variant was similar in both groups and across the different stroke subtypes. The ANP gene G664A polymorphism is therefore unlikely to be an important risk factor for ischemic stroke in this population. |
| doi_str_mv | 10.1212/WNL.57.9.1726 |
| format | Article |
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The ANP gene G664A polymorphism is therefore unlikely to be an important risk factor for ischemic stroke in this population.</description><identifier>ISSN: 0028-3878</identifier><identifier>EISSN: 1526-632X</identifier><identifier>DOI: 10.1212/WNL.57.9.1726</identifier><identifier>PMID: 11706124</identifier><identifier>CODEN: NEURAI</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Aged ; Atrial Natriuretic Factor - genetics ; Biological and medical sciences ; Brain Ischemia - epidemiology ; Brain Ischemia - genetics ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Medical sciences ; Middle Aged ; Neurology ; Polymorphism, Single Nucleotide ; Risk Factors ; Stroke - epidemiology ; Stroke - genetics ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Neurology, 2001-11, Vol.57 (9), p.1726-1728</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-15f911656f8daef5d939ad71fc62117c462fbface76042d69c938e4ab8d192703</citedby><cites>FETCH-LOGICAL-c319t-15f911656f8daef5d939ad71fc62117c462fbface76042d69c938e4ab8d192703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14115034$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11706124$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HASSAN, A</creatorcontrib><creatorcontrib>ALI, N</creatorcontrib><creatorcontrib>DONG, Y</creatorcontrib><creatorcontrib>CARTER, N. 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The ANP gene G664A polymorphism is therefore unlikely to be an important risk factor for ischemic stroke in this population.</description><subject>Aged</subject><subject>Atrial Natriuretic Factor - genetics</subject><subject>Biological and medical sciences</subject><subject>Brain Ischemia - epidemiology</subject><subject>Brain Ischemia - genetics</subject><subject>Female</subject><subject>Genetic Predisposition to Disease</subject><subject>Genotype</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Risk Factors</subject><subject>Stroke - epidemiology</subject><subject>Stroke - genetics</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0028-3878</issn><issn>1526-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1PGzEQhq0K1KTAsVfkC9w2eLy79voYoZZWisoFBDfLsceN2_3C3kXKv8cokXKawzzz6p2HkO_AVsCB37382axquVIrkFx8IUuouShEyV_PyJIx3hRlI5sF-ZbSP8byUqqvZAEgmQBeLYldTzGYlvYmzzniFCwdcZyCQ_oXe6QPQlRrOg7tvhviuAupo6Z3dNohjSH9p4OnIdkddvnQYsRtHN5NsnNrInUhoUl4Sc69aRNeHecFef754-n-V7F5fPh9v94UtgQ1FVB7BSBq4Rtn0NdOlco4Cd4KngvbSnC_9caiFKziTiirygYrs20cKC5ZeUFuD7ljHN5mTJPucjVsW9PjMCcteaYYqzNYHEAbh5Qiej3G0Jm418D0p1WdrepaaqU_rWb--hg8bzt0J_qoMQM3RyC_blofTW9DOnEVQM3KqvwAhdWAIA</recordid><startdate>20011113</startdate><enddate>20011113</enddate><creator>HASSAN, A</creator><creator>ALI, N</creator><creator>DONG, Y</creator><creator>CARTER, N. 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D</creatorcontrib><creatorcontrib>MARKUS, H. S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HASSAN, A</au><au>ALI, N</au><au>DONG, Y</au><au>CARTER, N. D</au><au>MARKUS, H. S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease</atitle><jtitle>Neurology</jtitle><addtitle>Neurology</addtitle><date>2001-11-13</date><risdate>2001</risdate><volume>57</volume><issue>9</issue><spage>1726</spage><epage>1728</epage><pages>1726-1728</pages><issn>0028-3878</issn><eissn>1526-632X</eissn><coden>NEURAI</coden><abstract>The atrial natriuretic peptide (ANP) gene may underlie stroke susceptibility and sensitivity to cerebral ischemia in an animal model of stroke. The authors investigate its role in humans by genotyping a polymorphism (G664A) in 436 patients with ischemic cerebrovascular disease and 295 community control subjects. The frequency of this variant was similar in both groups and across the different stroke subtypes. The ANP gene G664A polymorphism is therefore unlikely to be an important risk factor for ischemic stroke in this population.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>11706124</pmid><doi>10.1212/WNL.57.9.1726</doi><tpages>3</tpages></addata></record> |
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| ispartof | Neurology, 2001-11, Vol.57 (9), p.1726-1728 |
| issn | 0028-3878 1526-632X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete; Alma/SFX Local Collection |
| subjects | Aged Atrial Natriuretic Factor - genetics Biological and medical sciences Brain Ischemia - epidemiology Brain Ischemia - genetics Female Genetic Predisposition to Disease Genotype Humans Male Medical sciences Middle Aged Neurology Polymorphism, Single Nucleotide Risk Factors Stroke - epidemiology Stroke - genetics Vascular diseases and vascular malformations of the nervous system |
| title | Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease |
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