In vivo sodium iodide symporter gene therapy of prostate cancer

Radioiodine therapy, the most effective form of systemic radiotherapy available, is currently useful only for thyroid cancer because of thyroid-specific expression of the sodium iodide symporter (NIS). Here we explore the efficacy of a novel form of gene therapy using adenovirus-mediated in vivo NIS...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Gene therapy 2001-10, Vol.8 (20), p.1524-1531
Hauptverfasser:	SPITZWEG, C, DIETZ, A. B, O'CONNOR, M. K, BERGERT, E. R, TINDALL, D. J, YOUNG, C. Y. F, MORRIS, J. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - radiotherapy Adenocarcinoma - therapy Adenoviridae - genetics Adenovirus Adenoviruses Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Applied cell therapy and gene therapy Artificial Gene Fusion - methods Biological and medical sciences Biotechnology Blotting, Western - methods Cell Line Cytomegalovirus Fundamental and applied biological sciences. Psychology Gene therapy Gene transfer Genetic Therapy - methods Genetic Vectors - administration & dosage Health. Pharmaceutical industry Humans Immunohistochemistry - methods Industrial applications and implications. Economical aspects Iodine Radioisotopes - metabolism Iodine Radioisotopes - therapeutic use Male Medical sciences Mice Mice, Nude Neoplasm Transplantation NIS gene Prostate cancer Prostatic Neoplasms - metabolism Prostatic Neoplasms - radiotherapy Prostatic Neoplasms - therapy Radiation therapy Sodium iodide Sodium iodide symporter Symporters - genetics Symporters - metabolism Thyroid cancer Thyroid gland Transfection - methods Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation, Heterologous Tumors Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!