Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel

Rel/NF-kappaB transcription factors control a variety of cellular processes, such as cell growth and apoptosis, that are relevant to oncogenesis, and mutations in genes encoding Rel/NF-kappaB transcription factors have been found in several human lymphoid cell cancers. In this study, we have used a...

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Veröffentlicht in:	Oncogene 2001-10, Vol.20 (48), p.7098-7103
Hauptverfasser:	GILMORE, Thomas D, CORMIER, Catherine, JIMS, Jean-Jacques, GAPUZAN, Maria-Emily
Format:	Artikel
Sprache:	eng
Schlagworte:	Agar Animals Apoptosis Apoptosis - genetics Bcl-2 protein bcl-X Protein Biological and medical sciences c-Rel protein Care and treatment Cell Line, Transformed Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cell Transformation, Neoplastic - genetics Chickens Colony-Forming Units Assay - methods Culture Media DNA binding proteins Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Neoplastic Gene mutations Genes, bcl-2 Genes, rel Genetic aspects Genetic transformation Health aspects Humans Lymphomas Mice Molecular and cellular biology NF-kappa B - physiology NF-κB protein Oncogene Proteins v-rel - physiology Physiological aspects Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - physiology Proto-Oncogene Proteins c-rel - genetics Proto-Oncogene Proteins c-rel - physiology Recombinant Fusion Proteins - physiology Signal Transduction Species Specificity Spleen Spleen - cytology Transcription factors Transcription, Genetic Transfection Tumorigenesis
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